Cerebellar anaplastic astrocytoma in a teenager with Ollier Disease.

Journal of Neuro-oncology
Mohammad Sami Walid, Earl Christopher Troup

Abstract

Ollier Disease is a sporadic skeletal disorder with a predisposition to oncogenesis. It is estimated at around 1/100,000. We are presenting a young patient with Ollier Disease and high-grade astrocytoma. A 14-year-old, Caucasian male with Ollier Disease presented with a history of headaches, vomiting, blurred vision, and unsteady gait. Brain MRI with contrast showed a 41 x 55 mm mass in the posterior fossa with spotty enhancement, which pathology proved to be anaplastic astrocytoma. Despite the universal acceptance that Ollier Disease carries a high risk of developing malignancy there is very little in the literature about systematic screening. We recommended a cost-effective screening regime for these patients.

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Citations

Mar 28, 2009·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Luca D'AngeloConcezio Di Rocco
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