Nov 13, 2019

Cerebellar Arteriovenous Malformation with Coexistent Hemangioblastoma

World Neurosurgery
Jorge A Monserrate MarreroCaleb Feliciano


This is a case of a man aged 40 years with a past medical history of smoking, hypertension, polycythemia vera, intellectual disability, and schizophrenia who presented with generalized headaches, progressive loss of balance, and visual disturbance for 1 month. Head computed tomography and magnetic resonance imaging revealed a right cerebellar hematoma associated to heterogenous lesion with cystic components and flow-voids in the right cerebellar hemisphere. A ventriculoperitoneal shunt was placed with partial improvement of symptoms. Further vascular studies confirmed presence of a vascular nidus with significant arteriovenous shunting. The patient later required intervention for cerebellar arteriovenous malformation (AVM) removal. Microscopic evaluation of the lesion showed the AVM nidus, as well as large, vacuolated stromal cells and numerous thin-walled vessels. Immunostaining with inhibin and S-100 highlighted the stromal cells with numerous lipid-containing vacuoles. The earlier mentioned findings were consistent with the diagnosis of an AVM with coexistent hemangioblastoma of the right cerebellar hemisphere. Coexistence of hemangioblastomas and AVMs are extremely rare, and only 3 cases have been reported previously in the...Continue Reading

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Mentioned in this Paper

Magnetic Resonance Imaging
Blood Vessel
Neoplastic Vacuolated Stromal Cell
Recombinant Inhibins
Hypertensive Disease

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