Cerebellar cortical dysplasia: MRI aspects and significance

Journal de radiologie
G Soto AresJ P Pruvo

Abstract

Because it is now possible to obtain high-resolution multiplanar MR imaging of the cerebellum and because of the developing interest on the role of the cerebellum on higher brain functions, we have decided to study the process of cerebellar fissuration. All brain MRI examinations performed in children for varied neurological and neurosurgical indications, especially children with non-specific mental retardation and patients with cerebral malformation detected at initial imaging work-up, were reviewed. Fissuration and lobulation anomalies (abnormal orientation of fissures, pseudopolymicrogyria, cortical thickening, subcortical cysts and heterotopia) were identified that we called cerebellar cortical dysplasia (CCD). In order to better understand the origin of this malformation, current data on cerebellar embryogenesis and histogenesis will be reviewed, and the pathological and radiological features will be illustrated. Milder forms of CCD represent a distinct group of anomalies that should be distinguished from other types of cerebellar dysplasia (agenesis, hypoplasia or complex dysplasia with involvement of the cerebellar vermis (rhombencephalosynapsis)) or combined cerebellar and cerebral dysplasia (muscular dystrophies and li...Continue Reading

References

Aug 7, 1978·Acta Neuropathologica·R L Friede, J Mikolasek
Aug 23, 1991·Brain Research·D Wahlsten, M Andison
Dec 17, 1991·Brain Research. Developmental Brain Research·M SekiguchiR S Nowakowski
Jul 1, 1991·Behavior Genetics·P A CooperJ K Hewitt
Feb 1, 1987·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·P G Barth
Oct 1, 1968·Developmental Medicine and Child Neurology·L B RorkeH E Riggs
Nov 1, 1994·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·A K ShettyD E Phillips
Nov 1, 1993·Journal of Neuropathology and Experimental Neurology·G LyonE Della Giustina
Aug 1, 1993·Developmental Dynamics : an Official Publication of the American Association of Anatomists·J A Napieralski, L M Eisenman
Jan 1, 1993·Brain Research Bulletin·D E Lorke, W Niedermauntel
Feb 11, 1997·Pediatrics·V W SwayzeN C Andreasen
Mar 1, 1997·Journal of the American Academy of Child and Adolescent Psychiatry·B J CaseyJ L Rapoport
Jan 1, 1997·Annual Review of Neuroscience·K Herrup, B Kuemerle
Nov 21, 1997·Nature·N Ben-ArieH Y Zoghbi
Apr 2, 1999·Neurology·E Courchesne
Sep 17, 1999·Journal of Child Neurology·K J MillenM E Hatten
Feb 26, 2000·Proceedings of the National Academy of Sciences of the United States of America·L M ParsonsP T Fox
Mar 17, 2000·Brain Research. Brain Research Reviews·F A Middleton, P L Strick
Mar 29, 2000·Brain : a Journal of Neurology·R A Carper, E Courchesne
May 11, 2000·The Journal of Comparative Neurology·F Mercier, G I Hatton

❮ Previous
Next ❯

Citations

Nov 26, 2009·Brain : a Journal of Neurology·A James BarkovichWilliam B Dobyns
Jan 29, 2011·Journal of Child Neurology·Irene ToldoPier Antonio Battistella
Nov 26, 2015·Journal of Computer Assisted Tomography·Ahmed Abdel Khalek Abdel Razek, Mauricio Castillo

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Neuroradiology. Journal De Neuroradiologie
P Jissendi TchofoG Soto Ares
AJNR. American Journal of Neuroradiology
A J Barkovich
Journal of Neuroradiology. Journal De Neuroradiologie
E SilitT Ozturk
© 2022 Meta ULC. All rights reserved