Cerebellar Degeneration-related Antigen 1 Is Ubiquitously Expressed in Human Epidermis and Dermis.

Current Medical Science
Lu-Lu WangErwin Tschachler

Abstract

Cerebellar degeneration-related antigen 1 (CDR1) was described to be expressed in the nervous system and in different types of cancer tissues. In the present study, we demonstrate that CDR1 is in addition ubiquitously expressed in human epidermis, dermis and isolated skin cells. Both CDR1 mRNA and protein were detected in human skin-derived mast cells, melanocytes, fibroblasts and keratinocytes, suggesting that CDR1 does not have a neuron-specific function.

References

Apr 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·Y T ChenL J Old
Apr 1, 1989·Proceedings of the National Academy of Sciences of the United States of America·H M FurneauxJ B Posner
Aug 15, 1986·Cell·R L Eckert, H Green
Jul 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·E J DropchoL J Old
Dec 25, 2013·The International Journal of Biological Markers·Michele SalemiAldo E Calogero
Apr 30, 2014·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Paolo BoscoMichele Salemi

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