PMID: 9193144Jan 1, 1997Paper

Cerebellar nuclei: the olivary connection

Progress in Brain Research
T J Ruigrok

Abstract

This chapter gives an overview of the relation between the inferior olive and the cerebellar nuclei based on tracing and electrophysiological experiments in rats and cats. The olivary and cerebellar nuclear masses appear to maintain a precise topographical relationship. The olivary projection to the cerebellar nuclei is strictly contralateral, originates as climbing fiber collaterals, and is excitatory. The cerebellar projection to the inferior olive is exactly reciprocal to the olivonuclear projection, but, in addition, also has a variable but definite ipsilateral component, and has been demonstrated to be GABAergic. Stimulation and lesion experiments carried out in cat imply that the cerebellar nucleo-olivary pathway may be involved in regulating the oscillatory capabilities of olivary cells and as such may also have an effect on the synchrony of olivary firing. Subsequent stimulation experiments performed in rats suggests that synchronous firing of olivary neurons may result in profound effects in cerebellar nuclear neurons.

Citations

Jan 30, 2015·Frontiers in Cellular Neuroscience·Hassan MarzbanMojgan Rastegar
Feb 24, 2001·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·T Uno, M Shibata
Dec 25, 2004·Journal of Applied Physiology·Qiuli Liu, Margaret T T Wong-Riley
Jun 23, 2006·Nature Reviews. Neuroscience·Narender Ramnani
Apr 17, 2010·Proceedings of the National Academy of Sciences of the United States of America·Freek E HoebeekChris I De Zeeuw
Aug 21, 2009·Nature Reviews. Neuroscience·Richard Apps, Richard Hawkes
Apr 17, 2010·The Cerebellum·Reza TadayonnejadRay W Turner
Apr 28, 2011·The Journal of Physiology·Marylka Uusisaari, Erik De Schutter
Apr 9, 2013·The Cerebellum·Vincenzo PerciavalleRaudel Sánchez-Campusano
Sep 15, 2010·The Cerebellum·Nadia L Cerminara, Richard Apps
Nov 18, 2014·Frontiers in Systems Neuroscience·Eric J LangIzumi Sugihara
Mar 11, 2006·The Cerebellum·Fredrik Bengtsson, Germund Hesslow
Sep 1, 2005·Experimental Brain Research·P SvenssonG Hesslow
Dec 8, 2004·The European Journal of Neuroscience·F BengtssonG Hesslow
May 18, 2006·The Journal of Comparative Neurology·Luis HerreroRichard Apps
Jun 5, 2004·Progress in Neurobiology·Daniela CarulliPiergiorgio Strata

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