Cerebellopontine angle tumors in infants and children

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
T Tomita, Gordan Grahovac

Abstract

Cerebellopontine angle (CPA) and cerebellomedullary fissure (CMF) tumors are rare in children and information is scarce in the literature. This retrospective study reports their histological distribution and tumor origin, and describes surgical resections and post-operative outcome based upon the authors' consecutive personal series. Clinical data of infants and children 16 years old or younger of age treated from 2001 to 2012 by a single surgeon was retrospectively reviewed. All had histologically verified CPA/CMF tumors and underwent radical tumor resection through craniotomy except for two children who had a stereotactic biopsy for malignant tumors (glioblastoma and primitive neuroectodermal tumor (PNET)). Tumors' pathological distributions, tumors' origin, surgical approaches, and patients' outcome were reviewed. There were 44 infants and children with the age at diagnosis ranging from 11 weeks to 16 years; 32 were predominantly in the CPA and/or CMF whereas 12 showed an extension to the fourth ventricle. Pathology showed 14 ependymomas, 12 benign gliomas (11 pilocytic astrocytomas, 1 ganglioglioma), 4 atypical teratoid rhabdoid tumors (ATRTs), 4 epidermoids, 3 primitive neuroectodermal tumors (PNETs), 3 meningiomas, 3 nerv...Continue Reading

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Citations

Oct 25, 2016·Neuro-Chirurgie·S BoissonneauP-H Roche
Mar 24, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Joel S KatzJeffrey R Leonard
Mar 4, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S Joy TrybulaTadanori Tomita
Mar 17, 2020·Journal of Pediatric Rehabilitation Medicine·Kaliani Lima CoçaMárcia Gonçalves Ribeiro
Sep 28, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Mairre James S GaddiAlaric Emmanuel M Salonga
Apr 10, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Eric A GoetheSandi Lam

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Methods Mentioned

BETA
surgical
biopsies
total resection
surgical resections

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