Cerebral activation related to implicit sequence learning in a Double Serial Reaction Time task

Brain Research
F H C E Van Der GraafB M De Jong

Abstract

Using functional magnetic resonance imaging (fMRI), we examined the distribution of cerebral activations related to implicitly learning a series of fixed stimulus-response combinations. In a novel - bimanual - variant of the Serial Reaction Time task (SRT), simultaneous finger movements of the two hands were made in response to pairs of visual stimuli that were presented in a fixed order (Double SRT). Paired stimulus presentation prevented explicit sequence knowledge occurring during task practice, which implied that a dual task paradigm could be avoided. Extensive prescanning training on randomly ordered stimulus pairs allowed us to focus on the acquisition of implicit sequence knowledge. Activation specifically related to the acquisition of fixed sequence knowledge was highly significant in the right ventrolateral prefrontal cortex. The medial prefrontal and right ventral premotor cortex were more indirectly related with such procedural learning. We conclude that this set of activations reflects a stage of implicit sequence learning constituted by components of (i) spatial working memory (right ventral prefrontal cortex), (ii) response monitoring and selection (medial prefrontal cortex), and (iii) facilitated linkage of visuo...Continue Reading

References

Feb 1, 1990·Brain : a Journal of Neurology·U Halsband, H J Freund
Nov 1, 1989·Journal of Experimental Psychology. Learning, Memory, and Cognition·M A Stadler
Mar 15, 1994·The Journal of Comparative Neurology·M T LuP L Strick
Nov 1, 1993·Memory & Cognition·M A Stadler
Jun 17, 1993·Nature·J JonidesM A Mintun
Aug 20, 1996·Proceedings of the National Academy of Sciences of the United States of America·A M OwenA C Evans
Jan 1, 1997·Annual Review of Neuroscience·S P WiseR Caminiti
Mar 14, 1998·Proceedings of the National Academy of Sciences of the United States of America·A KarniL G Ungerleider
Jul 1, 1999·NeuroImage·K J FristonK J Worsley
Aug 10, 2000·Experimental Brain Research·R E PassinghamM F Rushworth
Aug 10, 2001·Psychonomic Bulletin & Review·A T Hsiao, A S Reber
Jan 24, 2002·Proceedings of the National Academy of Sciences of the United States of America·Julien DoyonLeslie G Ungerleider
Oct 1, 1995·Journal of Cognitive Neuroscience·S T GraftonR Ivry

❮ Previous
Next ❯

Citations

Aug 30, 2008·Journal of Cognitive Neuroscience·Rebecca M C Spencer, Richard B Ivry
May 6, 2009·Journal of Cognitive Neuroscience·Joseph M GaleaR Chris Miall
Mar 23, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·M W StenekesB M de Jong
Apr 6, 2007·NeuroImage·Hiske van DuinenInge Zijdewind
Oct 1, 2013·Neurobiology of Learning and Memory·Elisabeth A KaruzaRichard N Aslin
Dec 17, 2008·Journal of Neuropsychology·Marian E BerryhillIngrid R Olson
Jun 16, 2011·Human Brain Mapping·Anne B Kühn, Ricarda I Schubotz
Oct 16, 2007·Brain Research·Phan LuuRoy Stripling
Aug 23, 2008·Brain Research·Martijn KeitzKlaus L Leenders
Nov 4, 2008·Brain Research·Hillary Schwarb, Eric H Schumacher
Jan 22, 2013·Neuroscience and Biobehavioral Reviews·Evelien NackaertsAlice Nieuwboer
Jun 6, 2019·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Rodrigo C MarquesAmaury Cantilino

❮ Previous
Next ❯

Related Concepts

Related Feeds

Basal Ganglia

Basal Ganglia are a group of subcortical nuclei in the brain associated with control of voluntary motor movements, procedural and habit learning, emotion, and cognition. Here is the latest research.

Related Papers

Journal of Cognitive Neuroscience
Amanda Bischoff-GretheS T Grafton
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
Russell A PoldrackBarbara J Knowlton
Journal of Cognitive Neuroscience
S T GraftonRichard B Ivry
© 2021 Meta ULC. All rights reserved