Cerebral Blood Flow and Its Connectivity Deficits in Mild Traumatic Brain Injury at the Acute Stage.

Neural Plasticity
Fengfang LiXindao Yin

Abstract

The influence of cognitive impairment after mild traumatic brain injury (mTBI) on cerebral vascular perfusion has been widely concerned, yet the resting-state cerebral blood flow (CBF) connectivity alterations based on arterial spin labeling (ASL) in mild traumatic brain injury (mTBI) remain unclear. This study investigated region CBF and CBF connectivity features in acute mTBI patients, as well as the associations between CBF changes and cognitive impairment. Forty-five acute mTBI patients and 42 health controls underwent pseudocontinuous arterial spin labeling (pCASL) perfusion magnetic resonance imaging (MRI). The alterations in regional CBF and relationship between the CBF changes and cognitive impairment were detected. The ASL-CBF connectivity of the brain regions with regional CBF significant differences was also compared between two groups. Neuropsychological tests covered seven cognitive domains. Associations between the CBF changes and cognitive impairment were further investigated. Compared with the healthy controls, the acute mTBI patients exhibited increased CBF in the bilateral inferior temporal gyrus (ITG) and decreased CBF in the right middle frontal gyrus (MFG), the bilateral superior frontal gyrus (SFG), and th...Continue Reading

References

Oct 1, 1995·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·B BiswalJ S Hyde
Apr 9, 2005·Journal of the American Geriatrics Society·Ziad S NasreddineHoward Chertkow
Sep 1, 2007·NeuroImage·John Ashburner
Apr 29, 2010·Magnetic Resonance Imaging·Sina Aslan, Hanzhang Lu
Sep 15, 2012·NeuroImage·Lester Melie-GarcíaCarlos Sánchez-Catasús
May 23, 2013·Acta Physiologica·A MicarelliM Pagani
May 16, 2014·Applied Neuropsychology. Adult·Elaine de GuiseMitra Feyz
Feb 5, 2015·Developmental Neuropsychology·Yang WangBrenna C McDonald
Mar 31, 2015·Journal of Psychiatric Research·Jiajia ZhuChunshui Yu
Jun 7, 2015·Experimental Neurology·Kimbra KenneyRamon Diaz-Arrastia
Mar 30, 2016·Current Neurology and Neuroscience Reports·Yousef Hannawi, Robert D Stevens
Jun 7, 2016·Journal of the International Neuropsychological Society : JINS·Mary R NewsomeHarvey S Levin
Aug 25, 2016·Journal of Neurotrauma·Karen M BarlowR Marc Lebel
Oct 30, 2016·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·Anna E LeeuwisWiesje M van der Flier
Aug 11, 2017·NeuroImage. Clinical·Nathan W ChurchillTom A Schweizer
Nov 24, 2017·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Peter JezzardThomas W Okell
Jan 10, 2018·Acta Radiologica·Inger HavsteenAnders F Christensen
Apr 4, 2018·Journal of Neurotrauma·Margalit HaberDanielle Sandsmark
Jul 18, 2018·Journal of Neurotrauma·Sarah B RockswoldChristophe Lenglet
Jul 18, 2018·Journal of Neuroradiology. Journal De Neuroradiologie·Mai-Lan Ho
Jan 9, 2019·Frontiers in Neurology·Suzanne PolinderNicole von Steinbuechel
Mar 25, 2019·Frontiers in Neurology·Maíra Glória de Freitas CardosoAline Silva Miranda
Oct 28, 2019·Journal of Neurotrauma·Julia HamerTom A Schweizer
Jan 7, 2020·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Andrew B DoddAndrew R Mayer
Jan 25, 2020·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Nora A HerwegMichael J Kahana

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Software Mentioned

SPSS
GAUSSIAN
ASL
DARTEL
SPM8

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Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.