Cerebral blood flow in moyamoya disease. Part 2: Autoregulation and CO2 response

Acta neurochirurgica
A OgawaJ Suzuki

Abstract

In order to clarify the cerebrovascular response in Moyamoya disease, the autoregulation and CO2 response was investigated using the 81mKr continuous cerebral blood flow (CBF) measurement technique. A total of 32 measurements were made over the anterior and posterior circulation in 16 Moyamoya patients (seven adults, nine children). CBF measurements were made during four loading trials (hypertension, hypotension, CO2 inhalation and hyperventilation). Study was then made of the vascular response of the frontal lobe, perfused by the internal carotid artery (ICA), and the occipital lobe and cerebellum, perfused by the vertebral artery (VA). Deficits of autoregulation were more severe among the juvenile cases in response to hypotension than to hypertension in both the ICA and VA regions, but the deficits were mild. The CO2 response to hypercapnea in the juvenile cases tended to be abnormal in both the ICA and VA regions. Both adult and juvenile patients showed deficits in the ICA region in response to hyperventilation, some of whom exhibited paradoxial responses. Notable differences in the severity of the deficits of the vascular response in adult and juvenile cases were seen, with the deficits in the response being more severe amo...Continue Reading

References

Mar 1, 1979·Neurologia Medico-chirurgica·A Nishimoto
Jan 1, 1979·Archives of Neurology·N KodamaJ Suzuki
Nov 1, 1978·Journal of Neurosurgery·J KarasawaT Sakaki
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Jan 1, 1986·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·M KameyamaT Ido
Sep 1, 1974·Stroke; a Journal of Cerebral Circulation·L D IliffL Symon
Jul 1, 1984·Stroke; a Journal of Cerebral Circulation·H SekiJ Suzuki
Jul 1, 1983·Stroke; a Journal of Cerebral Circulation·A OgawaJ Suzuki
Jan 1, 1964·The American Journal of Physiology·M REIVICH

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Citations

Dec 31, 1997·Clinical Neurology and Neurosurgery·C C HungC J Shih
Dec 31, 1997·Clinical Neurology and Neurosurgery·H OshimaT Yamamoto
Oct 7, 2010·Journal of Neurosurgical Anesthesiology·Tariq ParraySaif Siddiqui
Jun 5, 2013·CNS Neuroscience & Therapeutics·Jie ChenShan Gao
Mar 20, 2013·Paediatric Anaesthesia·Jennifer K LeeEdward S Ahn
Oct 23, 2008·Lancet Neurology·Satoshi Kuroda, Kiyohiro Houkin
Jul 1, 2010·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Marco LeeGary K Steinberg
May 22, 2008·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Matthias ReinhardAndreas Hetzel
Oct 5, 2007·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kevin VinecoreBrahm Goldstein
Jul 8, 2003·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Soo Mee LimYoung Shin Ra
Feb 17, 2000·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·J C SunC R Honey
Oct 1, 1995·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·S KurodaK Mitsumori

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