Cerebral Blood Flow Measurement by Near-Infrared Spectroscopy During Carotid Endarterectomy

Journal of Neurosurgical Anesthesiology
Shinya KatoYoshihiko Ohnishi

Abstract

It is crucial to evaluate cerebral blood flow (CBF) during carotid endarterectomy (CEA). However, it is difficult to measure CBF in the operating room. The recent development of high-accuracy near-infrared spectroscopy (NIRS) has enabled the measurement of regional CBF following injection of indocyanine green (ICG). We aimed to measure changes in regional CBF by clamping the carotid artery during CEA and to analyze factors affecting the blood flow index (BFI) in CEA. Patients undergoing elective CEA were enrolled in this study after it was approved by the institutional ethical board. All patients underwent CEA under general anesthesia. Intraoperative blood pressure was controlled about 30% higher than the precarotid cross-clamping during carotid cross-clamping. ICG (0.5 mg/kg) was injected before, during, and after carotid cross-clamping. The kinetics of an intravenous bolus of ICG were monitored by a NIRS oximeter (NIRO200NX) and the BFI was calculated using the slope of the ICG concentration. The impact of carotid cross-clamping on the BFI was evaluated, along with factors influencing changes in the BFI. A total of 50 patients were enrolled. The BFI significantly decreased during carotid cross-clamping compared with baseline ...Continue Reading

References

Jul 23, 1977·Lancet·D J ThomasE Zilkha
Aug 15, 1991·The New England Journal of Medicine·UNKNOWN North American Symptomatic Carotid Endarterectomy Trial CollaboratorsM Eliasziw
Mar 1, 1991·Annals of Neurology·W J Powers
Dec 1, 1995·Stroke; a Journal of Cerebral Circulation·M KaminogoM Yonekura
Apr 16, 1998·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·W M KueblerA E Goetz
Sep 10, 1999·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·J E DalmanR G Ackerstaff
Dec 3, 1999·Stroke; a Journal of Cerebral Circulation·M J HartkampW P Mali
Jan 22, 2003·Intensive Care Medicine·Bendicht P WagnerJuerg Pfenninger
Jan 1, 1964·The American Journal of Physiology·M REIVICH
Aug 12, 2009·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C W A PennekampG J de Borst
Dec 7, 2010·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·S BouriA H Davies
Feb 11, 2011·Stroke; a Journal of Cerebral Circulation·Frank L SilverUNKNOWN CREST Investigators
Oct 6, 2011·Current Opinion in Anaesthesiology·Claire W A PennekampGert Jan de Borst
Dec 24, 2011·Journal of Neurology, Neurosurgery, and Psychiatry·Teddy Y WuP Alan Barber
Jan 24, 2012·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·C W A PennekampG J de Borst
Jun 13, 2014·Journal of Neurosurgical Anesthesiology·Kyung Y YooJongUn Lee

❮ Previous
Next ❯

Citations

Feb 23, 2017·Journal of Neurosurgical Anesthesiology·Jeffrey J Pasternak, William L Lanier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.