Cerebral Blood Volume During Neonatal Transition in Term and Preterm Infants With and Without Respiratory Support

Frontiers in Pediatrics
Bernhard SchwabergerBerndt Urlesberger

Abstract

Background: Recently, we demonstrated that in healthy newborn infants cerebral blood volume (CBV) was decreasing continuously after birth. We hypothesized that this was due to the increase in oxygen delivery to the brain during neonatal transition. Thus delayed cerebral oxygen delivery in infants in need for respiratory support (RS) during postnatal stabilization might influence changes in CBV. Objective: Aim of the study was to evaluate transitional changes in CBV immediately after birth in term and preterm infants with and without need of RS. Methods: We performed a post-hoc analysis of data collected as primary and secondary outcome parameters in prospective observational studies and randomized controlled trials at the Medical University of Graz (Austria). NIRS measurements by using "NIRO 200-NX" (Hamamatsu, Japan) were carried out over the first 15 min after birth in term and preterm infants delivered by cesarean section with and without requirement for RS. Results: In 204 neonates, we observed a significant decrease in CBV within the first 15 min after birth (p < 0.001) with a trend toward smaller ΔCBV in neonates receiving RS (p = 0.097) compared to neonates without RS. Differences of ΔCBV between groups reached statistic...Continue Reading

References

Jun 7, 2005·Early Human Development·Gorm Greisen
May 5, 2010·Pediatrics·Jennifer A DawsonColin J Morley
Jun 16, 2010·Archives of Disease in Childhood. Fetal and Neonatal Edition·Georg M SchmölzerPeter G Davis
Jun 17, 2010·Neonatology·David G SweetUNKNOWN European Association of Perinatal Medicine
Oct 20, 2010·The Journal of Pediatrics·Berndt UrlesbergerGerhard Pichler
Aug 20, 2011·Journal of Perinatology : Official Journal of the California Perinatal Association·H FuchsM B Schmid
Feb 26, 2013·The Journal of Pediatrics·Corinna BinderGerhard Pichler
Sep 23, 2014·Physiological Measurement·Bernhard SchwabergerBerndt Urlesberger
Feb 28, 2015·Developmental Neuroscience·Samantha K BartonTimothy J M Moss
Jun 13, 2015·Archives of Disease in Childhood. Fetal and Neonatal Edition·Nariae BaikGerhard Pichler
Sep 5, 2015·Neonatology·Bernhard SchwabergerBerndt Urlesberger
Sep 21, 2015·The Journal of Pediatrics·Mmoloki KenosiEugene M Dempsey
Feb 24, 2016·The Journal of Pediatrics·Bernhard SchwabergerBerndt Urlesberger
Apr 23, 2016·Neonatology·Samantha K BartonGraeme R Polglase

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Citations

Jul 28, 2018·Archives of Disease in Childhood. Fetal and Neonatal Edition·Andrew William Gill
Aug 15, 2020·Frontiers in Pediatrics·Christina Helene WolfsbergerGerhard Pichler
Oct 1, 2021·Scientific Reports·Aya MorimotoTakashi Kusaka

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Methods Mentioned

BETA
cesarean section

Software Mentioned

SPSS Statistics

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