Moyamoya disease was diagnosed as the cause of cerebral infarction in eight young adults (seven women, one man), aged 17-40 (mean 33) years. All had angiographic abnormalities characteristic of moyamoya disease. Single-photon emission tomography showed bilateral carotid circulation hypoperfusion and posterior circulation hyperemia in all seven patients with regional cerebral blood flow studies. All seven women had used oral contraceptives before cerebral infarction. Four patients were treated medically; one died of a second cerebral infarction 9 months after diagnosis. Four patients underwent superficial temporal-to-middle cerebral artery anastomosis; they did well. Moyamoya disease should be included in the differential diagnosis of cerebral infarction as well as intracranial hemorrhage in young adults, particularly women. A possible relation between moyamoya disease and oral contraceptive use deserves investigation.
Cerebral hemodynamics in patients with moyamoya disease. A study of regional cerebral blood flow by the 133Xe inhalation method
Occlusive disease of intracranial main arteries with collateral networks (moyamoya disease) in adults
Fibromuscular hyperplasia of internal carotid arteries. Stroke in a young adult complicated by oral contraceptives
Basilar artery occlusion, two angiographically demonstrated cases in young women using oral contraceptives
Natural history of moyamoya disease: comparison of activity of daily living in surgery and non surgery groups
Moyamoya disease: a clinical spectrum, literature review and case series from a tertiary care hospital in Pakistan.
Perfusion-weighted magnetic resonance imaging in adult moyamoya syndrome: characteristic patterns and change after surgical intervention: case report
Cerebral hemodynamics as a predictor of stroke in adult patients with moyamoya disease: a prospective observational study.
Intracranial atherosclerotic disease associated with moyamoya collateral formation: histopathological findings
Direct versus indirect revascularization procedures for moyamoya disease: a comparative effectiveness study
Absent middle cerebral artery signal in transcranial color-coded sonography: a reliable indicator of occlusion?
Unilateral supraclinoid internal carotid artery stenosis with moyamoya-like vasculopathy. Noninvasive assessments
Association of cerebral arteriovenous malformations and spontaneous occlusion of major feeding arteries: clinical and therapeutic implications
Moyamoya disease: a spectrum of clinical and radiological findings in a series of eight paediatric patients.
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