Cerebral ischemia as a presenting feature of intracranial aneurysms: a negative prognostic indicator in the management of aneurysms

Neurosurgery
Anil Nanda, Prasad S S V Vannemreddy

Abstract

Cerebral ischemia (stroke) can be a presenting clinical feature of intracranial aneurysms and may herald poor prognosis. A retrospective review of admissions for aneurysms over a 6-year period revealed that 12 patients (5%) had stroke or stroke-like presentations among 236 patients with intracranial aneurysms. Patient demographics, characteristics of aneurysms, and management were analyzed. Of 12 patients reviewed, nine had anterior circulation aneurysms. Two patients presented with subarachnoid hemorrhage and 10 with unruptured aneurysms. Eleven patients had stroke at the time of presentation, and five had a previous history of transient ischemic attacks. Ten patients had hypertension and eight were active smokers. The mean size of 10 aneurysms was 11.8 mm. Surgical extirpation of the aneurysms was performed in all cases. Four cases revealed thrombus in the aneurysm and one was atherosclerotic. The 6-month outcome was good in seven patients (58%) and fair in four patients (33%). One patient died. This outcome was significantly worse (P < 0.01) compared to that of good grade aneurysms in our database. Hypertension was a significant indicator of poor outcome (P < 0.02). Ischemic episodes as a presenting feature of intracranial a...Continue Reading

References

Nov 1, 1979·Radiology·A W DuncanL Caplan
Sep 1, 1978·The British Journal of Radiology·M SacherM Clavel
Nov 1, 1978·Stroke; a Journal of Cerebral Circulation·M R Roach
Jan 1, 1992·European Neurology·G ParentiF Marconi
Jan 1, 1973·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·H Krayenbühl
Dec 1, 1972·Journal of Neurosurgery·L W Conway, L W McDonald
May 1, 1973·Journal of Neurosurgery·S H Okawara
Jan 1, 1968·Progress in Brain Research·J N Taptas, P A Katsiotis
Jan 1, 1982·Journal of Neurosurgery·G R SutherlandM J Chamberlain
Jun 1, 1982·Surgical Neurology·S FukuokaI Hashimoto
Nov 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·I R WhittleM Besser
Sep 1, 1980·Journal of Neurosurgery·T SakakiS Utsumi
Oct 1, 1995·Stroke; a Journal of Cerebral Circulation·R D BrownleeB J Curry
May 1, 1994·Stroke; a Journal of Cerebral Circulation·T WatanabeT Yoshimoto
Aug 1, 1993·Journal of Neurosurgery·S JuvelaO Heiskanen
Jan 1, 1993·Acta neurochirurgica·F NüsselP Huber
Dec 29, 1998·The New England Journal of Medicine·UNKNOWN International Study of Unruptured Intracranial Aneurysms Investigators
Oct 10, 2001·Neurology·J A FriedmanD O Wiebers

❮ Previous
Next ❯

Citations

Dec 1, 2007·Clinical and Experimental Pharmacology & Physiology·Wei ZhangDing-Feng Su
May 4, 2010·Neurological Research·José E CohenRonen R Leker
Feb 25, 2009·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Nancy McLaughlin, Michel W Bojanowski
Aug 27, 2011·AJNR. American Journal of Neuroradiology·B GuillonH Desal
Jun 4, 2015·British Journal of Neurosurgery·Changhu RuanBoyong Mao
Oct 12, 2010·Clinical Neurology and Neurosurgery·L CalviereV Larrue
Nov 29, 2011·CNS Neuroscience & Therapeutics·Chu YangDing-Feng Su
Dec 10, 2015·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Antonio ArauzMarco Zenteno
Jul 28, 2018·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Andrew R Carey
Dec 4, 2020·Clinical Neurology and Neurosurgery·Alberto VandenbulckeGiulia Cossu
May 21, 2021·NMC Case Report Journal·Kazuaki OkamuraTakayuki Matsuo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aneurysm

Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Blood Clotting Disorders

Thrombophilia includes conditions with increased tendency for excessive blood clotting. Blood clotting occurs when the body has insufficient amounts of specialized proteins that make blood clot and stop bleeding. Here is the latest research on blood clotting disorders.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.