Cerebral ischemia associated with parenteral terbutaline use in pregnant migraine patients

American Journal of Obstetrics and Gynecology
K A RoseneT J Benedetti


Two pregnant patients with a history of migraine each developed evidence of cerebral ischemia while being treated with subcutaneous terbutaline, for asthma in one case and for tocolysis in the other. The evidence for cerebral ischemia as well as the occurrence of strokes associated with pregnancy or migraine is discussed. Mechanisms by which a selective beta 2 agonist could affect cerebral vasculature are unknown. Until more is known we recommend that pregnant patients with migraine or vascular headache not be given terbutaline.


Jul 17, 2014·Clinical Obstetrics and Gynecology·Janelle R Bolden
Jun 8, 2001·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·C Appere-De VecchiH Outin
Oct 27, 2004·Expert Opinion on Drug Safety·Peter G PrydeRobert Mittendorf
Aug 1, 1985·The Australian & New Zealand Journal of Obstetrics & Gynaecology·I IngemarssonS R Kottegoda
Jul 1, 1986·Medical Toxicology·K M LulichJ W Paterson

Related Concepts

Crescendo Transient Ischemic Attacks
Subcutaneous Injections
Premature Obstetric Labor
Status Migrainosus
Pregnancy Complications, Cardiovascular
Terbutalin von ct

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