PMID: 16528203Mar 11, 2006Paper

Cerebral vascular autoregulation assessed by perfusion-CT in severe head trauma patients

Journal of Neuroradiology. Journal De Neuroradiologie
Max WintermarkP Schnyder

Abstract

To use perfusion-CT technique in order to characterize cerebral vascular autoregulation in a population of severe head trauma patients with features of cerebral edema either on the admission or on the follow-up conventional noncontrast cerebral CT. A total of 80 perfusion-CT examinations were obtained in 42 severe head trauma patients with features of cerebral edema on conventional noncontrast cerebral CT, either on admission or during follow-up. Perfusion-CT results, i.e. the regional cerebral blood volume (rCBV) and flow (rCBF), were correlated with the mean arterial pressure (MAP) measured during each perfusion-CT examination. Ratios were defined to integrate the concept of cerebral vascular autoregulation, and cluster analysis performed, which allowed identification of different subgroups of patients. MAP values and perfusion-CT results in these groups were compared using Kruskal-Wallis and Wilcoxon (Mann-Whitney) tests. Moreover, the functional outcome of the 42 patients was evaluated 3 months after trauma on the basis of the Glasgow Outcome Scale (GOS) score and similarly compared between groups. Three main groups of patients were identified: 1) 22 perfusion-CT examinations were collected in 13 patients, characterized by ...Continue Reading

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Citations

Apr 13, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nuj TontisirinMonica S Vavilala
Dec 13, 2007·La Radiologia medica·A CianfoniL Bonomo
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Feb 23, 2010·Seminars in Roentgenology·Ashley H Aiken, Alisa D Gean
May 10, 2008·Journal of Neuroradiology. Journal De Neuroradiologie·M WintermarkJ D Chien
Feb 5, 2008·Journal of Neuroradiology. Journal De Neuroradiologie·L McG SmithM Wintermark
Aug 22, 2013·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·Nathalie SalaMauro Oddo
Sep 19, 2012·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Alexander KeedyMax Wintermark
Sep 4, 2010·Journal of Magnetic Resonance Imaging : JMRI·E Mark HaackeDouglas H Smith
Nov 27, 2014·AJNR. American Journal of Neuroradiology·M WintermarkUNKNOWN American College of Radiology Head Injury Institute
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Jul 19, 2021·Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine·Djino KhakiJohan Ljungqvist
Apr 3, 2021·The Journal of Trauma and Acute Care Surgery·Hossam AbdouJonathan J Morrison

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