PMID: 7034656Jan 1, 1982Paper

Cerebromeningitis in immunosuppressed recipients of renal allografts

Annals of Surgery
N L TilneyT B Strom

Abstract

The experience with cerebromeningitis in recipients of 769 renal allografts occurring over a 20-year period has been reviewed. Eighteen patients developed this complication; an incidence of 2.7%. Clinical manifestations were often subtle, although fever occurred almost universally. Primary risk factors included diabetes mellitus, use of high dose steroids both as maintenance immunosuppression and as treatment for acute rejection, and coincident infections or complications. The responsible organisms were fungi; the overall mortality rate 44%. By recognizing individual patient types who are at potential high risk for this complication, earlier diagnosis and more prompt and aggressive therapy has diminished the mortality dramatically in the last several years.

References

Dec 14, 1978·The New England Journal of Medicine·N L TilneyJ P Merrill
Mar 1, 1977·Annals of Surgery·A G Diethelm
Jan 1, 1978·Archives of Surgery·N L AscherJ S Najarian
Oct 1, 1979·Annals of Surgery·J S NajarianB G Sommer
Jul 19, 1979·The New England Journal of Medicine·J E BennettD W Alling
Mar 1, 1976·Annals of Surgery·S B LeapmanS L Kountz
Oct 1, 1975·The Journal of Infectious Diseases·J P UtzS Shadomy
Apr 1, 1973·Journal of Neurosurgery·P VisudhiphanS Khantanaphar
May 1, 1973·The Journal of Infectious Diseases·R M Moore, R B Zehmer
Aug 1, 1974·The Journal of Infectious Diseases·P D HoeprichM J Winship
Mar 1, 1970·Medicine·R C YoungV T DeVita
Aug 1, 1970·Journal of Neurology, Neurosurgery, and Psychiatry·V E EdwardsJ H Tyrer
Feb 1, 1981·The American Journal of Medicine·R H RubinN E Tolkoff-Rubin
Jan 17, 1980·The New England Journal of Medicine·G Medoff, G S Kobayashi
Apr 1, 1964·Annals of Internal Medicine·P P CARBONEE FREI

❮ Previous
Next ❯

Related Concepts

Related Feeds

Aspergillosis

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.

Aspergillosis (ASM)

Aspergillosis is the name given to a wide variety of diseases caused by infection by fungi of the genus Aspergillus. Aspergillosis occurs in chronic or acute forms which are clinically very distinct. Most cases of acute aspergillosis occur in patients with severely compromised immune systems. Chronic colonization or infection can cause complications in people with underlying respiratory illnesses. Discover the latest research on aspergillosis here.