PMID: 6966324Apr 1, 1980Paper

Cerebrospinal fluid complement proteins in neurological disease

Journal of the Neurological Sciences
P Price, M L Cuzner

Abstract

CSF levels of C3 and C4 were similar in patients with no neurological disease, minor non-inflammatory conditions, degenerative disease and MS during relapse, but slightly lower in MS during remission and higher in patients with inflammation. All MS patients had low CSF levels of alpha 1-antitrypsin and high levels of IgG. The roles of local production and consumption of complement protein and damage to the blood-brain barrier are discussed.

References

May 18, 1978·Journal of Neurology·G Schliep, K Felgenhauer
Jul 1, 1979·Journal of the Neurological Sciences·P Price, M L Cuzner
Feb 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·V J StecherG J Thorbecke
Jan 1, 1972·Acta Neurologica Scandinavica·H Link
Dec 10, 1969·Annals of the New York Academy of Sciences·S RuddyK F Austen
Jan 1, 1971·Humangenetik·F Kueppers

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Citations

Jun 15, 1987·Clinica Chimica Acta; International Journal of Clinical Chemistry·S S AsgharH J van der Helm
Jun 1, 1992·Journal of Neuroimmunology·S R BarnumE N Benveniste
Sep 5, 1998·Brain Research. Brain Research Reviews·P F StahelT Kossmann
Dec 2, 2008·Clinical and Experimental Immunology·G IngramB P Morgan
Nov 1, 1986·The American Journal of the Medical Sciences·V J Quagliarello, W M Scheld

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