PMID: 8953673Jan 1, 1996Paper

Cerebrospinal fluid filtration in a case of severe pneumococcal meningitis

Scandinavian Journal of Infectious Diseases
M BrizziB Hindfelt

Abstract

Current therapy of bacterial meningitis includes high doses of antibiotics and, sometimes, addition of corticosteroids in order to reduce a harmful inflammatory response. The persisting high mortality and rate of sequelae, particularly regarding pneumococcal meningitis, calls for new therapeutic approaches. We report a case of a 71-year-old female with a pneumococcal meningitis treated with extra-corporeal filtration of cerebrospinal fluid (CSF) after 3 days of coma on conventional treatment. The treatment was carried out without complications and the clinical outcome was favourable. We suggest that filtration of the CSF should be considered as a tool to eliminate noxious substances playing a harmful role in deteriorating course of bacterial meningitis.

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Citations

Jun 7, 2013·Neurocritical Care·Yasser B AbulhasanJeanne Teitelbaum
May 8, 2002·International Journal of Nursing Practice·Ulla MuinonenIan Peate
Oct 10, 2015·Neurology, Psychiatry, and Brain Research·Karl Bechter, Helene Benveniste

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