Abstract
Cerebrospinal fluid (CSF), with its protein markers, is a formidable material for investigating the relationships among the various cell types involved during the initial phase of plaque formation, or, successively, in the remyelination process. Its analysis may give definite help in better focusing on therapeutic objectives and therapeutic tools. Therefore, the possible use of CSF MBP, S-100, GFAP, N-CAM, NGF, and CNTF in pathogenetic studies and in clinical follow-up is critically reviewed. The need for correct interpretation of the data, for uniformity and reliability of the analytical methods, and for easy access to them is stressed. CSF examination and MRI should not be considered as alternative tools, or in competition, but should be used together, to take the maximum advantage of their individual possibilities.
References
Oct 1, 1977·Neurology·J N Whitaker
Nov 23, 1992·Neuroscience Letters·L B LaudieroU Otten
Mar 1, 1992·Annals of Neurology·D L ArnoldJ P Antel
Dec 1, 1990·Italian Journal of Neurological Sciences·A R MassaroP Tonali
Mar 1, 1985·Italian Journal of Neurological Sciences·A R MassaroP Bergonzi
Jun 1, 1988·Journal of Neurochemistry·S Bhat, D H Silberberg
Jun 14, 1988·Brain Research·S Bhat, D H Silberberg
Feb 1, 1985·Journal of Neurochemistry·M AlbrechtsenE Bock
Jul 1, 1980·Annals of Neurology·S R CohenG M McKhann
Aug 1, 1983·Journal of the Neurological Sciences·K MokunoI Sobue
Dec 1, 1982·Journal of Neurology, Neurosurgery, and Psychiatry·C J SindicP L Masson
Mar 1, 1995·Neurology·M FilippiG Comi
Mar 1, 1994·Italian Journal of Neurological Sciences·A R MassaroL Callegaro
Aug 1, 1994·Journal of Neurology, Neurosurgery, and Psychiatry·M AnderssonM Grønning
Jan 29, 1993·Science·J C LouisS Varon
Jan 1, 1996·Annals of Neurology·D H MillerJ Simon
Feb 1, 1996·Journal of Neuroscience Research·S D D'SouzaJ P Antel
Jan 1, 1997·European Neurology·A R MassaroA Carnevale
Citations
Oct 8, 1998·Multiple Sclerosis : Clinical and Laboratory Research·A R Massaro
Jun 11, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·Keiko KawamotoHiroshi Matsuda
May 7, 2004·The Journal of Trauma·Qingsong WangJianxin Jiang
Nov 27, 2007·Journal of Neurochemistry·Andrew K OttensKevin K W Wang
Dec 15, 2010·Drugs·Aaron BosterMichael K Racke
Jun 17, 2008·Current Opinion in Neurology·Michael K Racke
Apr 9, 2016·Current Opinion in Neurology·Pierre-Paul Axisa, David A Hafler
Sep 13, 2012·Journal of the Neurological Sciences·Barry W FestoffSharon Lynch
Aug 21, 2021·Autoimmunity Reviews·Staley A Brod