Cerebrospinal fluid shunt infection: risk factors and long-term follow-up

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Matthieu Vinchon, Patrick Dhellemmes

Abstract

Shunt infection (SI) is an enduring problem in pediatric neurosurgery. Its occurrence is variable in the different series that were published, according to the definition retained. In addition, long-term data, which could help to evaluate the incidence of delayed SI, as well as the developmental outcome after SI, are scarce in the literature. We reviewed retrospectively children shunted for hydrocephalus during the last 20 years to evaluate the incidence of SI, including late SI, the risk factors and sources of contamination, and the late outcome after SI. We treated 1,173 patients who were followed-up for a mean duration of 7.0 years. During that period, 158 patients presented with a total number of 190 episodes of infection, 19 of which occurred more than 1 year after surgery. The infection rates per patient and per procedure were 13.6 and 5.9%, respectively. Age below 4 months at shunt insertion [odds ratio (OR)=1.81], antenatal diagnosis (OR=2.23), myelomeningocele (OR=2.14), and post-hemorrhagic hydrocephalus (OR=1.98) were significantly correlated with SI. SI was mostly due to intraoperative contamination; however, delayed SI was mostly caused by blood-borne contamination and abdominal sepsis. The mortality related to SI ...Continue Reading

References

Dec 1, 1979·Journal of Neurosurgery·R GeorgeM Epstein
Dec 1, 1992·Journal of Neurosurgery·M ChouxG Lena
Jul 1, 1992·Journal of Neurosurgery·I K PopleR D Hayward
Jan 1, 1985·Pediatric Neuroscience·D B ShurtleffP W Hayden
Apr 1, 1981·Journal of Neurology, Neurosurgery, and Psychiatry·B JennettN Brooks
Dec 1, 1984·Journal of Neurosurgery·D RenierJ F Hirsch
May 1, 1984·Journal of Neurosurgery·B C WaltersR P Humphreys
Mar 1, 1995·Australian Veterinary Journal·J M Cox
Apr 29, 1999·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·A J MangramW R Jarvis
Feb 22, 2000·Pediatric Neurosurgery·C BairdT Pittman
Feb 24, 2001·Journal of Neurosurgery·A V KulkarniM Lamberti-Pasculli
Sep 19, 2002·The Pediatric Infectious Disease Journal·Rachel T SchrefflerRobert R Wittler
Oct 9, 2002·Neuropediatrics·M VinchonP Dhellemmes
Mar 26, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Matthew J McGirtDaniel J Sexton
Jul 24, 2003·Pediatric Neurosurgery·Matthieu VinchonPatrick Dhellemmes
Nov 12, 2003·Journal of Neurosurgery·Soma T GovenderJames R van Dellen

❮ Previous
Next ❯

Citations

Apr 13, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Eva-Karin PerssonPaul Uvebrant
Nov 6, 2008·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Scott L ParkerGeorge I Jallo
Mar 12, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dorte ClemmensenClaus Mosdal
Dec 30, 2011·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·G E BreimerE W Hoving
Apr 29, 2011·Current Infectious Disease Reports·Sheethal Laxmi, Allan R Tunkel
Jan 15, 2010·The New England Journal of Medicine·Diederik van de BeekAllan R Tunkel
Dec 3, 2009·The Pediatric Infectious Disease Journal·Sanda SardelicJulije Mestrovic
Aug 20, 2011·The Pediatric Infectious Disease Journal·Teresa J TuanTamara D Simon
Feb 16, 2012·The Pediatric Infectious Disease Journal·Tamara D SimonNicole Mayer Hamblett
Jul 9, 2010·Clinical Microbiology Reviews·Matthijs C BrouwerDiederik van de Beek
Jan 31, 2008·Pediatric Neurosurgery·Daniel M SciubbaGeorge I Jallo
Aug 29, 2012·Fluids and Barriers of the CNS·Matthieu VinchonAbhaya V Kulkarni
May 4, 2010·Journal of Neurosurgery. Pediatrics·Ken R Winston, Vinay Bhardwaj
Jun 3, 2009·Journal of Neurosurgery. Pediatrics·Ken R WinstonLori A McBride
Jun 3, 2009·Journal of Neurosurgery. Pediatrics·Farid RadmaneshHasan Eftekhar Ardebili
Aug 4, 2009·Journal of Neurosurgery. Pediatrics·Tamara D SimonUNKNOWN Hydrocephalus Clinical Research Network
Jun 3, 2010·Journal of Neurosurgery. Pediatrics·Paul H LeliefeldL Jaap Kappelle
Sep 3, 2010·Journal of Neurosurgery. Pediatrics·Tamara D SimonJay Riva-Cambrin
Dec 3, 2011·Journal of Neurosurgery. Pediatrics·Daniel H FulkersonAndrew Jea
Dec 3, 2011·Journal of Neurosurgery. Pediatrics·Paul KlimoFrederick A Boop
Nov 3, 2012·Neurosurgical Focus·Judith M WongAtul A Gawande
May 21, 2013·Journal of Neurosurgery. Pediatrics·Meysam A KebriaeiJoshua J Chern
Oct 9, 2007·Journal of Neurosurgery·Robert W LenfesteyDaniel K Benjamin
Apr 2, 2008·Journal of Neurosurgery. Pediatrics·Daniel H Fulkerson, Joel C Boaz
Jun 4, 2008·Journal of Neurosurgery. Pediatrics·Regina EymannMichael Kiefer
Aug 21, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Benoit J M PirotteJacques Brotchi
Nov 19, 2008·British Journal of Neurosurgery·P SørensenK Poulsen
Mar 23, 2011·American Journal of Surgery·Emad AllamFrank E Johnson
May 26, 2009·International Journal of Radiation Oncology, Biology, Physics·Thomas E MerchantRaja B Khan
Apr 27, 2010·Special Care in Dentistry : Official Publication of the American Association of Hospital Dentists, the Academy of Dentistry for the Handicapped, and the American Society for Geriatric Dentistry·Fernanda Weber de Morais GallarretaGisele Faria
Aug 27, 2014·Journal of Neuroimmunology·Yenis Gutierrez-Murgas, Jessica N Snowden
Apr 15, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Nihat DemirOğuz Tuncer
Mar 31, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Giovanni RaffaAntonino Germanò
Oct 25, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Katia OrvinJacob Amir
Mar 26, 2014·The Journal of Pediatrics·Tamara D SimonUNKNOWN Hydrocephalus Clinical Research Network

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Caroline HayhurstConor L Mallucci
Journal of Neurosurgery
John R W KestleMarion L Walker
© 2021 Meta ULC. All rights reserved