Cerebrovascular accidents complicating transcatheter aortic valve implantation: frequency, timing and impact on outcomes

EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Stefan StorteckyPeter Wenaweser

Abstract

Cerebrovascular accidents (CVA) are considered among the most serious adverse events after transcatheter aortic valve implantation (TAVI). The objective of the present study was to evaluate the frequency and timing of CVA after TAVI and to investigate the impact on clinical outcomes within 30 days of the procedure. Between August 2007 and October 2011, 389 high-risk elderly patients with symptomatic severe aortic stenosis underwent TAVI via transfemoral, transapical or subclavian access. A total of 14 patients (3.6%) experienced at least one CVA within 30 days of follow-up and most events (74%) occurred within the first day of the procedure. Patients with CVA had an increased risk of all-cause (42.3% vs. 5.1%, ORadjusted 11.7, 95% CI 3.4-40.3, p<0.001) and cardiovascular mortality (38.4% vs. 4.6%, ORadjusted 10.5, 95% CI 2.9-37.8, p<0.001) compared to patients without CVA at 30 days of follow-up. Repeated device implantation attempts (ORadjusted 8.3, CI 2.1-33.3, p<0.003), chronic pulmonary disease (ORadjusted 4.7, CI 1.3-16.8, p=0.02) and body mass index <25 kg/m2 (ORadjusted 0.8, CI 0.7-0.9, p<0.01) emerged as independent predictors of periprocedural CVA. Cerebrovascular accidents among patients undergoing TAVI occur predomin...Continue Reading

References

Jan 1, 1994·Stroke; a Journal of Cerebral Circulation·R B D'AgostinoW B Kannel
Feb 18, 2005·European Heart Journal·Christian LundDavid Russell
Jul 30, 2010·The Annals of Thoracic Surgery·Giovanni FilardoPaul Grayburn
Oct 22, 2010·The New England Journal of Medicine·Martin B LeonUNKNOWN PARTNER Trial Investigators
Nov 23, 2010·JACC. Cardiovascular Interventions·Martin ArnoldJosef Ludwig
Nov 23, 2010·JACC. Cardiovascular Interventions·Fabian NietlispachJohn G Webb
Dec 28, 2010·Journal of the American College of Cardiology·Josep Rodés-CabauJohn G Webb
Jan 25, 2011·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Parla AstarciCécile Grandin
Jun 7, 2011·The New England Journal of Medicine·Craig R SmithUNKNOWN PARTNER Trial Investigators
Sep 21, 2011·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Gian Paolo UssiaCorrado Tamburino
Dec 24, 2011·JACC. Cardiovascular Interventions·Edgar L W TayJohn G Webb
Mar 7, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Holger EggebrechtRajendra H Mehta
Mar 10, 2012·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Christoph K NaberEberhard Grube
Mar 17, 2012·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Gabor ErdoesBalthasar Eberle

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Citations

Aug 2, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Stefan StorteckyStephan Windecker
Sep 18, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Christos V BourantasPatrick W Serruys
Sep 18, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Fabien Praz, Fabian Nietlispach
Sep 18, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Stefan StorteckyPeter Wenaweser
Sep 18, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Jean-Philippe Collet, Gilles Montalescot
Jan 9, 2014·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Christian ThiloAlbert M Kasel
Nov 22, 2013·The British Journal of Radiology·B ClaytonC Roobottom
Oct 9, 2013·Nature Reviews. Cardiology·Amir-Ali FassaAlec Vahanian
Feb 16, 2016·Journal of Clinical Ultrasound : JCU·Tomo AndoCynthia C Taub
Nov 26, 2015·Expert Review of Cardiovascular Therapy·Marco BarbantiDavide Capodanno
Feb 10, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Yan-Biao LiaoMao Chen
Dec 24, 2015·Journal of Thrombosis and Thrombolysis·Katia OrvinRan Kornowski
Oct 31, 2013·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Thomas F LüscherPatrick W Serruys
Mar 30, 2016·Current Atherosclerosis Reports·S Chris MalaisrieAndrei Churyla
Sep 19, 2015·Journal of the American College of Cardiology·Thomas Pilgrim, Stephan Windecker
Mar 20, 2015·Journal of the American College of Cardiology·Thomas WaltherUNKNOWN GARY Executive Board
Sep 27, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Norman MangnerAxel Linke
Apr 15, 2015·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Andreas BaumbachAlexandra J Lansky
Apr 16, 2013·Journal of the American College of Cardiology·Josep Rodés-CabauRichard C Becker
Sep 21, 2013·JACC. Cardiovascular Interventions·Pablo SalinasJose Luis Lopez-Sendon
Aug 12, 2014·Journal of Thrombosis and Thrombolysis·Abhishek SharmaJason Lazar
Apr 20, 2013·International Journal of Cardiology·Christos V BourantasPatrick W Serruys
May 14, 2016·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Peter WenaweserAlbrecht Elsässer
Jun 1, 2016·Interactive Cardiovascular and Thoracic Surgery·Stephanie GrabertSabine Bleiziffer
Oct 21, 2016·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Nicolas WernerUNKNOWN German Transcatheter Aortic Valve Interventions-Registry Investigators
Aug 16, 2016·Journal of the American College of Cardiology·Vincent AuffretJosep Rodés-Cabau
Mar 9, 2017·Expert Review of Cardiovascular Therapy·Hzr McConkeyS Redwood
Dec 3, 2014·Clinical Medicine Insights. Cardiology·Ioannis M Panayiotides, Evagoras Nikolaides
May 3, 2018·European Heart Journal·T J CahillB D Prendergast
Feb 26, 2013·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Tarun ChakravartyRaj Makkar
Aug 31, 2018·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Piera CapranzanoCorrado Tamburino
Nov 20, 2016·Journal of the American Heart Association·Thomas PilgrimStephan Windecker
Mar 15, 2014·Circulation Research·Christos V Bourantas, Patrick W Serruys
Jan 30, 2018·F1000Research·Mathias Van HemelrijckFrancesco Maisano

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