PMID: 16642449Apr 28, 2006Paper

Cerebrovascular disorders in preterm neonates

Revista de neurologia
A LegidoC D Katsetos

Abstract

To review the etiology, pathogenesis, clinical manifestations, diagnosis and treatment of cerebrovascular disorders (CVD) in preterm neonates. The germinal matrix-intraventricular hemorrhage (GM-IVH) is the most frequent intracranial hemorrhage. The pathogenesis includes intravascular, vascular and extravascular factors. The neuropathologic lesion is the hemorrhage within the subependymal GM. There are four degrees of severity. Clinical manifestations include three syndromes: catastrophic, saltatory and silent. Treatment is prophylactic. Periventricular hemorrhagic infarct is of venous origin, might be associated to GM-IVH and is difficult to differentiate from periventricular leukomalacia (PVL). Cerebellar hemorrhage frequency increases with decreasing gestational age. It may be asymptomatic or manifest with a non-specific neurologic picture. PVL is the most important ischemic lesion. Its pathogenesis includes anatomic, physiologic, maturational, biochemical, infectious and immunologic factors. The neuropathologic lesion is focal necrosis in the terminal distribution of the long penetrating arteries. Treatment is prophylactic. Other ischemic lesions are ischemic arterial infarct, cerebellar infarct, telencephalic leukoencephal...Continue Reading

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Acute Stroke

A stroke occurs when blood supply to the brain is interrupted depriving the brain of oxygen and nutrients. This feed focuses cerebrovascular accidents including ischemic and paralytic stroke.

Related Papers

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases
H YangS Zhu
Nutrition, Metabolism, and Cardiovascular Diseases : NMCD
Barbara V Howard, Marja-Riitta Taskinen
The Johns Hopkins Medical Letter Health After 50
© 2022 Meta ULC. All rights reserved