Cerebrovascular reactivity in patients with ruptured intracranial aneurysms

Journal of Neurosurgery
B VoldbyF T Jensen


The cerebral vasomotor reactivity to arterial hypotension and hypocapnia was studied in 34 patients between the 3rd and 13th day after rupture of an intracranial saccular aneurysm. Using the intra-arterial xenon-133 injection method, regional cerebral blood flow (rCBF) and cerebral metabolic rate of oxygen (CMRO2) were measured. The intraventricular pressure and cerebrospinal fluid (CSF) lactate and pH levels were determined. The degree of vasospasm was measured on angiograms taken immediately following the rCBF study. The patients were graded clinically according to the system of Hunt and Hess. Cerebral autoregulation was intact in patients in good clinical condition, but was impaired in patients in poor clinical condition. There was a close correlation between the degree of vasospasm and the degree of autoregulatory impairment, which varied from focal disturbances to global impairment. Intracranial hypertension and CSF lactic acidosis were commonly found in association with vasoparalysis. Cerebrovascular response to hyperventilation was generally preserved, although often reduced. During hyperventilation, the cerebral perfusion pressure became elevated, and increases in CMRO2 were often found, even in patients with severe dif...Continue Reading


Jan 1, 1991·Acta neurochirurgica·K OhnoY Matsushima
May 1, 1991·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·D P ArcherB I Tranmer
Oct 1, 1992·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·K AbeI Yoshiya
Aug 1, 1993·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·K Abe
Feb 28, 2006·Neurosurgical Review·R Loch Macdonald
Jul 31, 2013·Current Urology Reports·Giuseppe SimoneMichele Gallucci
Jul 1, 1989·Surgical Neurology·J I AusmanG Balakrishnan
Aug 1, 1993·Pharmacology & Therapeutics·J A Madden
Apr 16, 1998·Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism·K D YundtW J Powers
Sep 1, 1986·Journal of Neurosurgery·K F LindegaardH Nornes
Jun 1, 1993·Journal of Neurosurgery·Michael N DiringerR J Traystman
Apr 17, 2004·Journal of Neurosurgery·Brian A IulianoEdward H Oldfield
Jan 1, 1989·Acta neurochirurgica·W Hassler, F Chioffi
Mar 15, 2012·Progress in Neurobiology·Fatima A SehbaJohn H Zhang
May 31, 2008·International Journal of Oral and Maxillofacial Surgery·W S Choi, N Samman
May 23, 2008·Acta Anaesthesiologica Scandinavica·R G HoffC J Kalkman
Nov 19, 2013·Journal of Magnetic Resonance Imaging : JMRI·Leodante da CostaMichael Tymianski
Jul 1, 2006·Seminars in Ultrasound, CT, and MR·P C SanelliA Biondi
Jan 1, 1997·Critical Care Clinics·R E Adams, W J Powers


Feb 1, 1978·Journal of Neurosurgery·B K WeirC Rothberg
Sep 1, 1973·Journal of Neurosurgery·J Fein, R Boulos
Feb 1, 1973·Neuroradiology·G Du BoulayS H Shah
Jul 1, 1972·Journal of Neurosurgery·M P HeilbrunN A Lassen
Mar 1, 1972·Neurology·O B PaulsonM S Christensen
Jan 1, 1970·Pflügers Archiv : European journal of physiology·M WahlN A Lassen
Apr 1, 1968·The Tohoku Journal of Experimental Medicine·T KutsuzawaT Sato
Dec 1, 1983·Journal of Neurosurgery·K KamiyaL Symon
Dec 1, 1983·Annals of Neurology·R C HerosV Varsos
Jan 1, 1981·Stroke; a Journal of Cerebral Circulation·A D MendelowB H Eidelman
Jun 1, 1982·Journal of Neurosurgery·B Voldby, E Enevoldsen
Jul 1, 1965·Neurology·T W LANGFITTN F KASSELL
May 28, 1902·The Journal of Physiology·W M Bayliss

Related Concepts

Cerebral Blood Flow Imaging
Subarachnoid Hemorrhage, Spontaneous
Vasospasm, Intracranial
Cerebrospinal Fluid
Intracranial Aneurysm
Lactic Acid Measurement

Related Feeds


Aneurysms are outward distensions or bulges that occurs in a weakened wall of blood vessels. Discover the latest research on aneurysms here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.


Aphasia affects the ability to process language, including formulation and comprehension of language and speech, as well as the ability to read or write. Here is the latest research on aphasia.

Brain Ischemia

Brain ischemia is a condition in which there is insufficient blood flow to the brain to meet metabolic demand. Discover the latest research on brain ischemia here.

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.

© 2020 Meta ULC. All rights reserved