Jul 1, 1975

Certain problems of treatment of ischemic heart disease

I P ZamotaevB L Sandomirskiĭ


On the basis of extended personal experience and of the literature data, the authors give recommendations for differentiated rational drug therapy of different stages of ischaemic heart disease. The results of a study of comparative efficacy of 15 coronary-active drugs used in 709 patients with ischaemic heart disease are presented along with their clinical pharmacology, side effects, indications and counterindications. The conclusions were arrived at on the basis of an objective clinical and laboratory study of the effect of the drugs. The methods of evaluation of the drug's efficacy and of the selection of patients for the administration of adequate therapy are described, which permits to use these recommendations for practical purposes. Some problems of the pathogenesis of ischaemic heart disease are discussed in terms of the selection of pathogenetic therapy.

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Mentioned in this Paper

Myocardial Contraction
Pathogenic Aspects
Laboratory Studies
Clinical Pharmacology Discipline
Myocardial Ischemia
Coronary Arteriosclerosis
Cell Differentiation Process
Angina Pectoris
Drug Evaluation

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