PMID: 29782747Jan 1, 2016Paper

CERULOPLASMIN CORRECTION OF DYSLIPIDEMIA CAUSED BY CHRONIC PHYSICAL LOAD IN EXPERIMENT AT SUBMAXIMAL POWER

Eksperimental'naia i klinicheskaia farmakologiia
E N Ermolaeva, L V Krivokhizhina

Abstract

Chronic submaximal physical load of aerobic-anaerobic charater leads to pro-atherogenic dyslipidemia, as manifested by increased levels of triglycerides, total cholesterol, and very-low-density lipoproteins. Ceruloplasmin (total dose 60 mg/kg body weight, triple intraperitoneal introduction on the 1st, 3rd, and 5th day of experiment) produced a partial correction of dyslipidemia, manifested by restoration of the normal levels of triglycerides, total cholesterol, and lipoproteins of very low, low, and high density. At the same time, ceruloplasmin administration did not influence the level of phospholipids.

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