Cervical and intracranial atherosclerosis and silent brain infarction in Japanese patients with coronary artery disease

Cerebrovascular Diseases
Kazumi UekitaKenjiro Kikuchi

Abstract

To investigate the prevalence of cervical and intracranial atherosclerosis and silent brain infarction in patients with coronary artery disease (CAD). Cervical and intracranial atherosclerotic lesions on magnetic resonance angiography (MRA) and silent brain infarctions on magnetic resonance imaging (MRI) were investigated in comparison with the findings of coronary angiography in 133 consecutive patients with CAD. The mean severity scores of cervical and intracranial MRA lesions were significantly higher in the three-vessel CAD (0.40 and 0.53, respectively) than in the zero-vessel CAD group (0.04 and 0.11). The mean scores of the maximal size and multiplicity of MRI lesion were also significantly greater in the two-vessel (1.00 and 1.44) and three-vessel CAD (0.94 and 1.26) than in the zero-vessel CAD group (0.27 and 0.50). The incidence of MRA lesion was markedly higher in patients with brain MRI lesion than in those without (51.1 vs. 6.5%). Serious coronary artery lesions were commonly accompanied by latent atherosclerotic lesions in the cervical and intracranial arteries besides silent brain infarction in patients with CAD.

Citations

Jul 15, 2006·BMJ : British Medical Journal·Bruce Ovbiagele
Feb 26, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Atsushi HoshinoToshiharu Ijichi
Sep 21, 2010·Clinical Interventions in Aging·Jae-Sung Lim, Hyung-Min Kwon
Jun 22, 2007·Lancet Neurology·Sarah E VermeerPeter J Koudstaal
Mar 7, 2006·The Journal of Thoracic and Cardiovascular Surgery·Robert MoracaR Alan Hall
Apr 30, 2011·Journal of the American College of Cardiology·Eun-Jae LeeSun U Kwon
Jan 1, 2012·JRSM Cardiovascular Disease·Julia SlarkPankaj Sharma
Oct 15, 2014·Circulation·Katja RitzMat J A P Daemen
Sep 1, 2017·Journal of Atherosclerosis and Thrombosis·Akihiro TokushigeMitsuru Ohishi

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