Cervical Cancer Screening Guidelines in the Postvaccination Era: Review of the Literature

Journal of Oncology
Carlo A LiveraniAndrea Ciavattini

Abstract

Cervical cancer is relatively rare in high-income countries, where organized screening programs are in place, as well as opportunistic ones. As the human papillomavirus (HPV) vaccination rates increase, the prevalence of cervical precancers and cancers is going to decrease rapidly very soon, even if, in the most optimistic scenario, it is unlikely that optimal vaccination coverage will be achieved. Then, the optimal screening paradigm for cervical cancer prevention in the postvaccination era is still debated. Screening guidelines are being developed with the aim of reducing the number of tests a woman needs during her lifetime, in order to receive the maximum benefit from screening, while decreasing potential harms that may result with the use of a screening strategy (overdiagnosis, overtreatment, anxiety, and costs). With this purpose in mind, new management guidelines for cervical cancer screening abnormalities are recommendations based on risks, not on results. This review aims to summarize the process that led to the introduction of the HPV DNA test in screening programs and the different screening strategies. Moreover, it aims to introduce the new risk-based guidelines for the future, where full HPV genotyping can resize t...Continue Reading

References

Feb 26, 1999·Journal of the National Cancer Institute·P HolowatyT To
Jun 8, 2006·Journal of the National Cancer Institute·Guglielmo RoncoUNKNOWN New Technologies for Cervical Cancer Working Group
Jul 4, 2006·The Lancet Oncology·Guglielmo RoncoUNKNOWN New Technologies for Cervical Cancer screening Working Group
Oct 19, 2007·The New England Journal of Medicine·Pontus NauclerJoakim Dillner
Jan 9, 2008·The Journal of Infectious Diseases·Rachel L WinerLaura A Koutsky
Feb 6, 2008·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Laura Kotaniemi-TalonenPekka Nieminen
Sep 30, 2008·Journal of Lower Genital Tract Disease·L Stewart Massad
Nov 26, 2008·Vaccine·Raul MurilloEduardo Lazcano-Ponce
May 23, 2009·American Journal of Clinical Pathology·Diane SolomonUNKNOWN Cytopathology Education and Technology Consortium
Aug 22, 2009·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Marc ArbynBengt Andrae
Feb 24, 2010·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ArbynL von Karsa
May 4, 2010·Japanese Journal of Clinical Oncology·Chisato HamashimaUNKNOWN Japanese Research Group for Development of Cervical Cancer Screening Guidelines
Jul 2, 2010·Nature Reviews. Clinical Oncology·Philip E Castle
Jun 22, 2011·Obstetrics and Gynecology·Philip E Castle
Jun 28, 2011·International Journal of Cancer. Journal International Du Cancer·Sidsel Svennekjaer BarkenElsebeth Lynge
Jan 25, 2012·Journal of Cancer Research and Therapeutics·Divya HegdeSupriya Rai
May 25, 2012·International Journal of Cancer. Journal International Du Cancer·Marc ArbynJoseph Monsonego
Jun 20, 2012·Annals of Internal Medicine·Virginia A Moyer, UNKNOWN U.S. Preventive Services Task Force
Sep 8, 2012·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Luisa Lina Villa
Oct 12, 2012·Archives of Gynecology and Obstetrics·Daiki KobayashiTsuguya Fukui
Jan 9, 2013·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·James DickinsonUNKNOWN Canadian Task Force on Preventive Health Care
May 3, 2013·Obstetrics and Gynecology·L Stewart MassadUNKNOWN 2012 ASCCP Consensus Guidelines Conference
Jun 19, 2013·Journal of Lower Genital Tract Disease·Simon C LeesonK Ulrich Petry
Mar 13, 2014·American Journal of Clinical Pathology·Diane Davis DaveyUNKNOWN Cytopathology Education and Technology Consortium (CETC)
Apr 26, 2014·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Edyta C PirogUNKNOWN RIS HPV TT study group
Dec 9, 2014·International Journal of Cancer. Journal International Du Cancer·Margaretha A VinkJohannes Berkhof
Mar 5, 2016·South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde·N TathiahI Moodley
May 18, 2016·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·Sara FaragKatherine T Chen
Nov 9, 2016·Acta Cytologica·Laura W MusselwhiteAdhemar Longatto-Filho
Dec 30, 2016·Asian Pacific Journal of Cancer Prevention : APJCP·Kasturi JayantBhagwan Nene

❮ Previous
Next ❯

Citations

Apr 3, 2021·Gynecologic Oncology·Luca GiannellaAndrea Ciavattini
Jul 3, 2021·Viruses·Kendal RosalikJasmine Han

❮ Previous
Next ❯

Methods Mentioned

BETA
genotyping

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Journal of Clinical Virology : the Official Publication of the Pan American Society for Clinical Virology
Mariam El-ZeinEduardo L Franco
Obstetrics & Gynecology Science
Yung-Taek Ouh, Jae Kwan Lee
Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology
Nicolas Wentzensen, Stefanie J Klug
© 2021 Meta ULC. All rights reserved