Cervical cerclage placed before 14 weeks gestation in women with one previous midtrimester loss: A population-based cohort study

The Australian & New Zealand Journal of Obstetrics & Gynaecology
Margaret E HarphamAntonia W Shand

Abstract

Cervical cerclage is used in an attempt to reduce recurrence risk of preterm birth, but evidence for use is limited. To compare pregnancy outcomes among women with a single previous midtrimester delivery when managed with or without a cervical cerclage. Population-based cohort study of all women in New South Wales, Australia with a singleton pregnancy ending in birth/miscarriage ≥14 and <28 weeks, between 2003 and 2011. Modified Poisson regression was used to compare outcomes in the next subsequent pregnancy, for women with a cerclage inserted <14 weeks, and those without cerclage. The primary outcome was gestational age <37 weeks at birth/miscarriage in the next pregnancy. Secondary outcomes included: maternal morbidity, preterm prelabour rupture of membranes (PPROM), stillbirth/neonatal death and composite neonatal morbidity for liveborn infants ≥28 weeks. Adjusted risk ratios (ARR) and 95% confidence intervals (CI) were determined. Five thousand, six hundred and ninety-eight births/miscarriages were potential index deliveries. Of these, 2175 women had an eligible subsequent pregnancy: 108 received cerclage at <14 weeks gestation, 2067 did not. Women with cerclage were significantly more likely to deliver <37 weeks than those...Continue Reading

References

Aug 1, 1984·British Journal of Obstetrics and Gynaecology·R W RushA Grant
Aug 1, 1984·British Journal of Obstetrics and Gynaecology·P LazarE Papiernik
Mar 23, 2004·American Journal of Epidemiology·Guangyong Zou
Jun 9, 2004·Lancet·Meekai S ToUNKNOWN Fetal Medicine Foundation Second Trimester Screening Group
Oct 26, 2006·Medical Care·Toni HendersonVijaya Sundararajan
Mar 16, 2007·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Jodie M DoddCaroline A Crowther
Sep 2, 2008·Obstetrics and Gynecology·Michael S EsplinMichael W Varner
Jan 23, 2009·Paediatric and Perinatal Epidemiology·Christine L RobertsJonathan M Morris
Apr 21, 2011·Maternal and Child Health Journal·Samantha J LainChristine L Roberts
Apr 6, 2012·Lancet·Maria GoyaUNKNOWN Pesario Cervical para Evitar Prematuridad (PECEP) Trial Group
Apr 20, 2012·The Cochrane Database of Systematic Reviews·Zarko AlfirevicAndrea L Jorgensen
Sep 27, 2012·BMC Medical Research Methodology·Jason P BentleyChristine L Roberts
Aug 2, 2013·The Cochrane Database of Systematic Reviews·Jodie M DoddCaroline A Crowther
Jan 11, 2014·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Richard BrownUNKNOWN MATERNAL FETAL MEDICINE COMMITTEE
Jan 24, 2014·Obstetrics and Gynecology·UNKNOWN American College of Obstetricians and Gynecologists
Jul 1, 2014·Clinical Obstetrics and Gynecology·Anju Suhag, Vincenzo Berghella
Jul 29, 2015·American Journal of Obstetrics and Gynecology·Daphnie DrassinowerAlexander M Friedman

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Citations

May 18, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Patrik ŠimjákJiří Sláma
Apr 28, 2021·Minerva Obstetrics and Gynecology·Vito LeanzaMarco Palumbo

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