Cervical cytological abnormalities and factors associated with high-grade squamous intraepithelial lesions among HIV-infected women from Rio de Janeiro, Brazil

International Journal of STD & AIDS
Paula Mendes LuzBeatriz Grinsztejn

Abstract

Although cervical cancer remains a major public health problem in Brazil, knowledge of cervical cytological abnormalities among HIV-infected women remains scarce. At baseline evaluation of a cohort followed in Rio de Janeiro, Brazil, 703 HIV-infected women underwent cytology-based cervical cancer screening and human papillomavirus (HPV) DNA testing. Poisson regression analysis was used to evaluate the association of factors with the presence of high-grade squamous intraepithelial lesions (HSIL). Cervical cytology was abnormal in 24.3% of the women; 4.1% had HSIL. Beyond HPV infection, factors independently associated with the presence of HSIL was age (≥25 and ≤40 years, prevalence ratio [PR] 2.60, 95% confidence interval [CI] 1.11-6.10), and more than three pregnancies was protective (PR 0.33, 95% CI 0.11-0.94). High coverage of cervical cancer screening is warranted to prevent morbidity and mortality from cervical cancer in this population.

References

Feb 13, 2001·Diagnostic Cytopathology·E E CaloreM J Cavaliere
Mar 29, 2002·Journal of Clinical Pathology·F X BoschK V Shah
Nov 26, 2002·Virus Research·Silvia de Sanjosé, Joel Palefsky
Apr 11, 2003·Lancet·Jennifer S SmithValerie Beral
Mar 19, 2004·Cadernos de saúde pública·Luiz Augusto Marcondes FonsecaJosé Eluf Neto
Jul 22, 2004·Journal of the National Cancer Institute·Long Fu Xi, Nancy B Kiviat
Jul 22, 2004·Journal of the National Cancer Institute·Linda Ahdieh-GrantStephen J Gange
Feb 5, 2005·Cadernos de saúde pública·Luciane Kalakun, Mary Clarisse Bozzetti
Mar 17, 2005·Journal of the National Cancer Institute·Gary M CliffordUNKNOWN Swiss HIV Cohort
Apr 21, 2005·Journal of the National Cancer Institute·Howard D StricklerJoel M Palefsky
Aug 2, 2005·European Journal of Obstetrics, Gynecology, and Reproductive Biology·L NappiG Putignano
Oct 27, 2005·AIDS·Dayse Pereira CamposAngela Jourdan Gadelha
Dec 20, 2005·The Journal of Pathology·Peter J F SnijdersChris J L M Meijer
Feb 8, 2006·Cadernos de saúde pública·Maria do Carmo LealCélia Landmann Szwarcwald
Jul 6, 2006·International Journal of STD & AIDS·Beatriz GrinsztejnJudith S Currier
Aug 8, 2006·Lancet·Viviana SimonQuarraisha Abdool Karim
Sep 5, 2006·Vaccine·D Maxwell Parkin, Freddie Bray
Apr 18, 2007·British Journal of Cancer·V V SahasrabuddheG P Parham
May 22, 2007·Clinical Obstetrics and Gynecology·Thomas C Wright
Jul 14, 2007·Disease Markers·F Xavier Bosch, Silvia de Sanjosé
Jul 20, 2007·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Silvia Franceschi, Harold Jaffe
Sep 11, 2007·Lancet·Mark SchiffmanSholom Wacholder
Oct 9, 2007·Lancet·Guglielmo Ronco, Nereo Segnan
Dec 12, 2007·Cadernos de saúde pública·Maria Goretti P Fonseca, Francisco I Bastos
Feb 16, 2008·International Journal of STD & AIDS·Päivi LehtovirtaOskari Heikinheimo
Jul 18, 2008·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Beatriz GrinsztejnJoel Palefsky
Jul 30, 2008·International Journal of STD & AIDS·Somsamorn MangclavirajPraphan Phanuphak
Apr 3, 2009·The New England Journal of Medicine·Rengaswamy SankaranarayananKetayun A Dinshaw

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Citations

Nov 1, 2015·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Mary C CambouBeatriz Grinsztejn
Apr 11, 2015·Cadernos de saúde pública·Leonardo Soares BastosLuciane de Souza Velasque
Feb 3, 2018·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Carmine CarrieroAntonella Vimercati
Sep 3, 2013·Journal of Graduate Medical Education·Ana Marušić
Jul 19, 2013·International Review of Psychiatry·Deirdre Johnston
Oct 7, 2021·Expert Review of Anti-infective Therapy·Brenda Evelin Barreto da SilvaVictor Santana Santos

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BETA
hysterectomy

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