Cervical pessary for preventing preterm birth: a meta-analysis

The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
Zhen JinHong Yu

Abstract

To evaluate the efficacy of cervical pessary in the prevention of preterm birth and its influence on pregnancy and maternal outcomes, so as to provide a clinical basis for cervical pessary to prevent premature delivery. The databases of PubMed, Web of Science, CNKI, WanFang Data, etc, were used to search for the eligible articles. The relevant data were abstracted by two independent reviewers and performed with Stata 12.0. Pregnancy Result: the PTB rates of pessary and control group before 28, 32, 34, and 37 weeks were analyzed and the combined RR (95%CI) values were 0.78 (0.46, 1.31), 0.92 (0.67, 1.28), 0.74 (0.49, 1.13), and 0.79 (0.54, 1.15). Compared with the control group, the utilization rate of tocolytic and corticosteroids was decreased 21% (RR = 0.79, 95%CI = 0.66-0.94) and 18% (RR = 0.82, 95%CI = 0.70-0.96). The risk of PROM and the difference was not statistically significant (p > .05). Subgroup analysis showed that there was no significant difference on the PTB rate subgroup and twins subgroup during 28 and 34 weeks (p > .05). The results showed that there was no significant difference on neonatal weight <1500 g and <2500 g (p > .05). Three articles on the average gestational age were included in the cervical length...Continue Reading

Associated Clinical Trials

References

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May 16, 2003·Journal of Perinatal Medicine·Birgit ArabinJim van Eyck
Oct 14, 2005·Archives of Gynecology and Obstetrics·Ganesh AcharyaJan Martin Maltau
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Mar 26, 2016·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·Mariarosaria Di TommasoTullia Todros

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Citations

Nov 29, 2020·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Marie-Andrée HarveyJane A Schulz
Aug 24, 2019·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Marit L Bovbjerg, Sabrina Pillai
Feb 2, 2021·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sergey V BarinovGalina B Beznoshchenko
Nov 29, 2020·Journal of Obstetrics and Gynaecology Canada : JOGC = Journal D'obstétrique Et Gynécologie Du Canada : JOGC·Marie-Andrée HarveyJane A Schulz
Feb 7, 2020·American Journal of Obstetrics and Gynecology·Agustin Conde-AgudeloKypros H Nicolaides

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