Cervical ripening balloon with and without oxytocin in multiparas: a randomized controlled trial

American Journal of Obstetrics and Gynecology
Alison M BauerDavid N Hackney

Abstract

The optimal method for induction of labor for multiparous women with an unfavorable cervix is unknown. We sought to determine if induction of labor with simultaneous use of oxytocin and a cervical ripening balloon, compared with sequential use, increases the likelihood of delivery within 24 hours in multiparous women. We performed a randomized controlled trial from November 2014 through June 2017. Eligible participants were multiparous women with a vertex presenting, nonanomalous singleton gestation ≥34 weeks undergoing induction of labor. Women were excluded for admission cervical examination >2 cm, ruptured membranes, chorioamnionitis or evidence of systemic infection, placental abruption, low-lying placenta, >1 prior cesarean delivery, or contraindication to vaginal delivery. Patients were randomly allocated to the following cervical ripening groups: simultaneous (oxytocin with cervical ripening balloon) or sequential (oxytocin following cervical ripening balloon expulsion). The primary outcome was delivery within 24 hours of cervical ripening balloon placement. Secondary outcomes included induction-to-delivery interval, time to cervical ripening balloon expulsion, mode of delivery, and adverse maternal or neonatal outcomes....Continue Reading

Citations

Oct 18, 2019·The Cochrane Database of Systematic Reviews·Marieke Dt de VaanMichel Boulvain
Feb 1, 2020·Current Opinion in Obstetrics & Gynecology·Michelle Solone, Kate A Shaw
Nov 15, 2019·F1000Research·Anna Maria Marconi
Aug 6, 2021·American Journal of Perinatology·Maria AndrikopoulouUNKNOWN Eunice Kennedy Shriver National Institute of Child Health Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU) Net
Mar 3, 2020·American Journal of Perinatology·Rodney K EdwardsJennifer D Peck
Oct 18, 2021·American Journal of Obstetrics & Gynecology MFM·Georgios DoulaverisVincenzo Berghella

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