Cervical Screening Results Leading to Detection of Adenocarcinoma in Situ of the Uterine Cervix

Asian Pacific Journal of Cancer Prevention : APJCP
Santipap SrisomboonJatupol Srisomboon

Abstract

Background: Adenocarcinoma in situ (AIS) of the uterine cervix is a preinvasive lesion of the invasive adenocarcinoma. We analyzed the cervical screening results leading to detecting the AIS lesions including the coexistence of AIS lesions with high-grade squamous intra-epithelial lesions (HSIL) and invasive carcinoma. Methods: Women who were diagnosed and received treatment for AIS at Chiang Mai University Hospital between January 1, 2007 and August 31, 2016 were retrospectively reviewed. The inclusion criteria were the women who had pathological diagnosis of AIS obtained from cervical punch biopsy or excisional cone biopsy with either loop electrosurgical excision procedure (LEEP) or cold-knife conization (CKC). The patient characteristics, diagnostic work-up and treatment details were reviewed, including the cervical screening results prior to the diagnosis of cervical AIS, pathologic results of excisional cone biopsy and hysterectomy specimens. Results: During the study period, 75 women with AIS pathology undergoing excisional cone biopsy with either LEEP (n=62) or CKC (n=13) were identified. The abnormal cytologic screening leading to detection of AIS was the squamous cell abnormality accounting for 57.3%. Abnormal glandul...Continue Reading

Citations

Jun 29, 2021·Cytopathology : Official Journal of the British Society for Clinical Cytology·Manolis NikolopoulosManish K Maheshwari

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Methods Mentioned

BETA
contraception
biopsy
hysterectomy

Software Mentioned

SPSS

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