Cervical screening: why young women should be encouraged to be screened

The Journal of Family Planning and Reproductive Health Care
Amanda HerbertAli A Kubba

Abstract

The English National Health Service Cervical Screening Programme (NHSCSP) recommendation not to offer cervical screening to women aged 20-24 years is considered in the context of national rates of cervical intraepithelial neoplasia grade 3 (CIN3) and invasive cervical carcinoma, falling screening coverage in young women, detection of screen-detected invasive cancers and risks of excisional treatment of CIN. Registrations of invasive and in situ cervical carcinoma were obtained from the Office for National Statistics, data on screening coverage and cytology results from the NHSCSP website and data on screen-detected cancers from an audit at Guy's & St Thomas' NHS Foundation Trust (GSTFT). Before and after the introduction of organised screening in England, CIN3 was primarily detected in women aged 20-39 years. Increasing rates of CIN3 were recorded in women aged 20-24 years during the last decade (3000-4000 cases per year) despite falling screening coverage. The peak incidence of invasive cancer in screening age groups is now 35-39 years. At GSTFT in 1999-2006, 24 of 32 cancers (75%) in women aged 20-34 years were screen-detected and that percentage declined in subsequent 15-year age bands (p < or =0.0001). Delaying the age for ...Continue Reading

References

Jul 1, 1992·British Journal of Obstetrics and Gynaecology·P TidburyD Jenkins
Jul 1, 1991·Gynecologic Oncology·R PretoriusN Fotheringham
Jun 1, 1995·American Journal of Public Health·D T JanerichA P Polednak
Apr 6, 1996·Lancet·A SzarewskiJ Cuzick
Oct 1, 1996·American Journal of Obstetrics and Gynecology·R M DeMay
Feb 18, 1998·International Journal of Cancer. Journal International Du Cancer·A P VizcainoD M Parkin
Jul 2, 1999·Cytopathology : Official Journal of the British Society for Clinical Cytology·A Herbert, J A Smith
Mar 21, 2001·Cytopathology : Official Journal of the British Society for Clinical Cytology·A HerbertJ A Smith
Dec 14, 2001·Lancet·K WellingsJ Field
Oct 21, 2003·International Journal of Cancer. Journal International Du Cancer·Cornelis J A HogewoningChris J L M Meijer
May 6, 2004·JAMA : the Journal of the American Medical Association·Lynn SadlerLesley McCowan
Jul 21, 2004·Lancet·Julian PetoFiona E Matthews
Dec 3, 2004·Cancer Research·Chandrika J PiyathilakeEdward E Partridge
Mar 16, 2005·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Freddie BrayD Max Parkin
Jun 1, 2005·BJOG : an International Journal of Obstetrics and Gynaecology·Peter H SykesDavid J Peddie
Jun 24, 2006·Journal of Medical Screening·G C RieckA N Fiander
Sep 5, 2006·Vaccine·Henry C KitchenerJ Thomas Cox
Nov 7, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·F BruinsmaM Quinn
Jan 24, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Kristjan Sigurdsson, Helgi Sigvaldason
Nov 14, 2007·Journal of Obstetrics and Gynaecology : the Journal of the Institute of Obstetrics and Gynaecology·M S NairA J Nordin

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Citations

Jul 1, 2009·BMC Public Health·Amanda DeeksHelena Teede
Oct 24, 2013·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Jonathan J RolisonPi-Ju Liu
Oct 11, 2008·International Journal of Cancer. Journal International Du Cancer·Peter SasieniD Max Parkin
Apr 18, 2009·BJOG : an International Journal of Obstetrics and Gynaecology·A HerbertN Singh
Jul 31, 2009·International Journal of Cancer. Journal International Du Cancer·Amanda HerbertAli Kubba
Aug 7, 2013·Scientific Reports·Alexander LabeitAbbi Kedir
Jun 10, 2008·Clinical Oncology : a Journal of the Royal College of Radiologists·M Stanley
Apr 10, 2009·The Journal of Family Planning and Reproductive Health Care·Margaret Stanley
Apr 10, 2009·The Journal of Family Planning and Reproductive Health Care·Sue Perankin
Jun 12, 2019·Diagnostic Cytopathology·Cristina Díaz Del ArcoMª Jesús Fernández Aceñero
Mar 4, 2014·Journal of Clinical Nursing·Juanna SheaSandra Mackey
Oct 6, 2015·Asian Pacific Journal of Cancer Prevention : APJCP·Moza Al-KalbaniHans Nagar

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