Cervical spinal chordoma with chondromatous component in a dog

Veterinary Pathology
A GruberA Url

Abstract

A 7-year-old male Belgian Shepherd dog was presented with sudden onset of lateral recumbency and tetraparesis. At the level of the third cervical vertebra, magnetic resonance imaging demonstrated an intrameningeal and intramedullary mass lesion. The animal was subsequently euthanatized. A necropsy revealed a semitranslucent solid mass infiltrating dorsal and ventral dura mater and the spinal cord. Histologic examination revealed a lobulated pleomorphic mass, mainly resembling undifferentiated cartilage interspersed by spindle-shaped and polygonal cells with highly vacuolated cytoplasm (physaliphorous cells). Immunohistochemistry of the tumor cells demonstrated dual expression of vimentin and cytokeratin. Based on the histologic and immunohistochemical results, the diagnosis of a chordoma with chondromatous component was made.

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Citations

Oct 25, 2011·Acta Veterinaria Scandinavica·Øyvind StigenCaroline P Åkesson
Aug 25, 2010·The Veterinary Clinics of North America. Small Animal Practice·Rodney S Bagley
Mar 15, 2015·The Journal of Veterinary Medical Science·Mizuki KuramochiJyoji Yamate
Mar 11, 2015·The Journal of Veterinary Medical Science·Toshie IseriFumihito Ohashi
Feb 5, 2015·The Journal of Veterinary Medical Science·Takeshi YuiHiroyuki Taniyama
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Jan 14, 2017·Probiotics and Antimicrobial Proteins·Majid MajlesiMohammad Hadi Eskandari

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