PMID: 8966355Aug 1, 1996Paper

Cesarean section in a patient with a congenital deficit of antithrombin III: apropos of a case

Revista española de anestesiología y reanimación
M C BenitoP Sánchez

Abstract

Antithrombin III (AT III) is a physiological inhibitor of coagulation. AT III deficit, whether congenital or acquired, results in a state of hypercoagulability characterized by recurring instances of venous thrombosis in young people. Although AT III levels normally change little during pregnancy, a deficit can be associated to the appearance of recurring thromboembolism and the need to perform cesarean section increases the risk. We report a cesarean section under general anesthesia in a patient with congenital AT III, reviewing the etiology and pathophysiology of this entity as well as its treatment.

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