Chain-length dependence of diblock copolymer micellization kinetics studied by stopped-flow pH-jump

The Journal of Physical Chemistry. B
Jingyan ZhangShiyong Liu

Abstract

A series of well-defined poly(ethylene oxide)- b-poly(2-(diethylamino)ethyl methacrylate) (PEO- b-PDEA) diblock copolymers containing PEO block of identical chain length and PDEA block with varying degrees of polymerization (DP, in the range of 32-154) were prepared via atom transfer radical polymerization (ATRP) employing a PEO-based macroinitiator (DP = 113). Upon a pH-jump from 3 to 12 under highly efficient stopped-flow mixing conditions, PEO- b-PDEA copolymers spontaneously form spherical micelles of increasing sizes and aggregation numbers ( N agg) with increasing PDEA chain lengths. Stopped-flow light scattering technique was used to probe the pH-induced micellization kinetics of PEO- b-PDEA copolymers, aiming to elucidate the PDEA chain-length effects on the unimer-to-micelle transition process. Upon a stopped-flow pH-jump from 3 to 12, the obtained dynamic traces can be well-fitted with double exponential functions. The calculated fast and slow characteristic relaxation times (tau 1 and tau 2) can be ascribed to the formation of quasi-equilibrium micelles (fast process) and subsequent relaxation into final equilibrium micelles (slow process), respectively. For PEO 113- b-PDEA 32 and PEO 113- b-PDEA 61, tau 2 is almost ...Continue Reading

References

Jul 29, 1998·Macromolecules·F J EsselinkG Hadziioannou
Oct 6, 2004·Langmuir : the ACS Journal of Surfaces and Colloids·J I AmalvyY Duccini
Jan 22, 2005·Faraday Discussions·Irina A Nyrkova, Alexander N Semenov
Feb 17, 2005·Journal of the American Chemical Society·Juan Rodríguez-Hernández, Sébastien Lecommandoux
Feb 24, 2005·Chemical Society Reviews·Carolina de Las Heras AlarconCameron Alexander
May 3, 2006·Langmuir : the ACS Journal of Surfaces and Colloids·Dave J AdamsAnthony C Weaver
Mar 6, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Amália MezeiTibor Gilányi
Aug 4, 2007·Science·Honggang CuiDarrin J Pochan
Jun 18, 2001·Angewandte Chemie·Shiyong LiuSteven P Armes

❮ Previous
Next ❯

Citations

Nov 15, 2013·Physical Chemistry Chemical Physics : PCCP·Jingyan ZhangShiyong Liu
Feb 26, 2009·Langmuir : the ACS Journal of Surfaces and Colloids·Hao LiuShiyong Liu
Sep 1, 2012·The Journal of Physical Chemistry. B·Gabriel LandazuriY Rharbi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.