Challenges and opportunities in the care of survivors of adolescent and young adult cancers.

Pediatric Blood & Cancer
Miranda M FidlerPaul C Nathan

Abstract

Adolescents and young adults (AYA) with cancer are an understudied group. Much of what is known about long-term outcomes after AYA cancer has been derived from cohorts of childhood cancer survivors, which seldom include patients at the older end of the AYA age spectrum. In general, AYA cancer survivors have a lower risk for premature mortality, subsequent primary neoplasms and chronic health conditions than childhood cancer survivors. However, AYA cancer survivors are vulnerable to psychosocial challenges, concerns about fertility and relationships and financial toxicity. No single model is optimal for the care of these survivors, but it is generally agreed that all survivors require a survivor care plan that promotes their adherence to evidence-based surveillance guidelines. There is a need to create survivor cohorts that include the full range of AYA ages and diagnoses to be able to address the many pressing questions that remain unanswered in this vulnerable population.

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Citations

Sep 17, 2019·International Journal of Cancer. Journal International Du Cancer·Niilo LiuhtoPäivi Lähteenmäki
Feb 1, 2020·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Romualdo Sciorio
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Oct 18, 2019·Journal of Adolescent and Young Adult Oncology·Rinat S NissimMary Elliott
Sep 21, 2019·Clinical Journal of Oncology Nursing·Rosemary Semler, Bridgette Thom
Apr 12, 2021·Journal of the National Cancer Institute·Amy D LuPaul C Nathan
Nov 3, 2020·Pediatric Clinics of North America·Michael HawkinsLindsay M Morton
Jul 10, 2021·Fertility and Sterility·Francesca FilippiMonica Terenziani
Oct 1, 2021·Journal of Cancer Survivorship : Research and Practice·Karen L SyrjalaK Scott Baker
Oct 13, 2021·International Journal of Epidemiology·Ruth L DiazMiranda M Fidler-Benaoudia
Nov 16, 2021·International Journal of Clinical Oncology·Kayo NakataIsao Miyashiro
Dec 6, 2021·Journal of the National Cancer Institute·Olga HussonJohn M Salsman
Jan 21, 2022·Journal of Adolescent and Young Adult Oncology·Meghan E McGradyRobin E Norris

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