Challenges and opportunity of recent genome editing and multi-omics in cyanobacteria and microalgae for biorefinery

Bioresource Technology
Way-Rong LinI-Son Ng

Abstract

Microalgae and cyanobacteria are easy to culture, with higher growth rates and photosynthetic efficiencies compared to terrestrial plants, and thus generating higher productivity. The concept of microalgal biorefinery is to assimilate carbon dioxide and convert it to chemical energy/value-added products, such as vitamins, carotenoids, fatty acids, proteins and nucleic acids, to be applied in bioenergy, health foods, aquaculture feed, pharmaceutical and medical fields. Therefore, microalgae are annotated as the third generation feedstock in bioenergy and biorefinery. In past decades, many studies thrived to improve the carbon sequestration efficiency as well as enhance value-added compounds from different algae, especially via genetic engineering, synthetic biology, metabolic design and regulation. From the traditional Agrobacterium-mediated transformation DNA to novel CRISPR (clustered regularly interspaced short palindromic repeats) technology applied in microalgae and cyanobacteria, this review has highlighted the genome editing technology for biorefinery that is a highly environmental friendly trend to sustainable and renewable development.

Citations

Oct 17, 2019·Marine Drugs·Luca AmbrosinoMaria Luisa Chiusano
Sep 13, 2020·Applied Microbiology and Biotechnology·Shuying FengYu Liu
Mar 3, 2020·Bioresource Technology·Kuan Shiong KhooWei-Hsin Chen
Mar 14, 2021·Bioresource Technology·Said Abu-GhoshDavid Iluz
Jun 20, 2020·Biotechnology Advances·Jinyu CuiWeiwen Zhang
May 30, 2021·Journal of Environmental Management·Mohammad Ali ZahedMaryam Badamaki

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR (general)

Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). CRISPR-Cas system enables the editing of genes to create or correct mutations. Discover the latest research on CRISPR here.

CRISPR for Genome Editing

Genome editing technologies enable the editing of genes to create or correct mutations. Clustered regularly interspaced short palindromic repeats (CRISPR) are DNA sequences in the genome that are recognized and cleaved by CRISPR-associated proteins (Cas). Here is the latest research on the use of CRISPR-Cas system in gene editing.