Abstract
The rapidly expanding use of electronic records in health-care settings is generating unprecedented quantities of data available for clinical, epidemiological, and cost-effectiveness research. Several challenges are associated with using these data for clinical research, including issues surrounding access and information security, poor data quality, inconsistency of data within and across institutions, and a paucity of staff with expertise to manage and manipulate large clinical data sets. In this article, we describe our experience with assembling a data-mart and conducting clinical research using electronic data from four facilities within a single hospital network in New York City. We culled data from several electronic sources, including the institution's admission-discharge-transfer system, cost accounting system, electronic health record, clinical data warehouse, and departmental records. The final data-mart contained information for more than 760,000 discharges occurring from 2006 through 2012. Using categories identified by the National Institutes of Health Big Data to Knowledge initiative as a framework, we outlined challenges encountered during the development and use of a domain-specific data-mart and recommend appr...Continue Reading
References
Jan 1, 1991·International Journal of Clinical Monitoring and Computing·R M GardnerH F Young
Aug 1, 1997·International Journal of Clinical Monitoring and Computing·J D DaltoL Egbert
Jun 1, 2000·Journal of the American Medical Informatics Association : JAMIA·J J Cimino
Apr 2, 2005·Journal of the American Medical Informatics Association : JAMIA·Nancy C NelsonReed M Gardner
Mar 3, 2007·Journal of the American Medical Informatics Association : JAMIA·David K VawdreyFrank A Drews
Oct 20, 2007·Journal of the American Medical Informatics Association : JAMIA·Stephen B JohnsonPeter Stetson
Oct 24, 2007·International Journal of Medical Informatics·Kristiina HäyrinenPirkko Nykänen
Oct 17, 2008·Nursing Outlook·Bonnie L WestraGail Keenan
Mar 27, 2009·The New England Journal of Medicine·David Blumenthal
Aug 12, 2009·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Michael A Jhung, Shailen N Banerjee
Feb 4, 2010·Medical Care·Eric G PoonDavid W Bates
Sep 30, 2010·Joint Commission Journal on Quality and Patient Safety·Timothy LandersElaine Larson
Jan 15, 2011·Journal of the American Medical Informatics Association : JAMIA·S Trent RosenbloomKevin B Johnson
Oct 28, 2011·Clinical and Translational Science·Mandar ApteElaine Larson
Dec 6, 2011·Surgical Infections·Mandar ApteElaine Larson
May 9, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Sameer J PatelElaine Larson
Jun 16, 2012·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Matthew J NeidellElaine L Larson
Jul 27, 2012·Journal of Diabetes and Its Complications·Christie Y JeonElaine L Larson
Sep 11, 2012·Journal of the American Medical Informatics Association : JAMIA·Caitlin M CusackLena Mamykina
Oct 3, 2012·PloS One·Christie Y JeonElaine L Larson
Oct 17, 2012·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Benjamin J MiriovskyAmy P Abernethy
Nov 13, 2012·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Christie Y JeonElaine Larson
Feb 22, 2013·Epidemiology and Infection·M Pogorzelska-MaziarzE L Larson
Apr 4, 2013·Epidemiology·Sengwee Toh, Richard Platt
Apr 4, 2013·JAMA : the Journal of the American Medical Association·Travis B Murdoch, Allan S Detsky
Apr 19, 2013·European Archives of Paediatric Dentistry : Official Journal of the European Academy of Paediatric Dentistry·H D Herman, M Ashkenazi
May 28, 2013·The Journal of Nursing Administration·Kathryn H BowlesMary D Naylor
Jun 19, 2013·Medical Care·William R HershJoel H Saltz
Feb 11, 2014·Journal of the American Medical Informatics Association : JAMIA·Lucila Ohno-Machado
Mar 19, 2014·Journal of Infection and Public Health·Caitlin M WolfeElaine Larson
Jul 10, 2014·Health Affairs·John D Halamka
Jan 1, 2013·EGEMS·William R HershJoel Saltz
Jun 5, 2015·American Journal of Infection Control·Kenrick D CatoElaine Larson
Citations
Jul 31, 2016·Healthcare : the Journal of Delivery Science and Innovation·Elise RussoHardeep Singh
Jan 4, 2017·Journal of Clinical Nursing·Gianfranco SansonFabio D'Agostino
Mar 24, 2016·Revista da Escola de Enfermagem da U S P·Rodrigo JensenMaria Madalena Januário Leite
Mar 19, 2019·Nursing Research·Jianfang LiuJingjing Shang
Oct 27, 2016·Oncotarget·Yushui MaDa Fu
Apr 6, 2019·Journal of Advanced Nursing·Allison SquiresSimon Jones
Apr 14, 2017·Surgical Infections·Kenrick D CatoElaine Larson
Jun 18, 2017·JMIR Medical Informatics·Morgan PriceJens Weber
Aug 29, 2020·European Journal of Epidemiology·Krishna Margadhamane GokhaleKrishnarajah Nirantharakumar
Oct 21, 2016·International Journal of Environmental Research and Public Health·Ho Ting WongAlice Yuen Loke
Jul 25, 2017·The Journal of Perinatal & Neonatal Nursing·Reeta LamminpääKatri Vehviläinen-Julkunen
Sep 19, 2020·Clinical Orthopaedics and Related Research·Rafa RahmanCasey J Humbyrd
May 15, 2021·Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews·Sarah M HannaKenneth R Gundle
May 28, 2021·Journal of Clinical Epidemiology·Omar DewidarGeorge A Wells
Jun 22, 2021·Journal of the American Medical Informatics Association : JAMIA·Lisiane PruinelliGyorgy Simon
Nov 3, 2021·JCO Clinical Cancer Informatics·Xia BiThomas R Klumpp
Mar 18, 2019·Journal of Biomedical Informatics·Bei LiXiaoyun Lan
May 25, 2021·Computers, Informatics, Nursing : CIN·Courtney OmaryRoy L Simpson