PMID: 9447604Feb 3, 1998Paper

Challenges in Duchenne muscular dystrophy

Neuromuscular Disorders : NMD
K E Davies

Abstract

The last seven years has witnessed an explosion in our understanding of the muscular dystrophies. In the early 1980s, prenatal diagnosis of Duchenne muscular dystrophy was developed. The cloning of the gene, in 1996, resulted in a better understanding of the disease process and led to the identification of a novel complex at the membrane. This information led to the cloning of other genes responsible for the autosomally inherited dystrophies. As we approach the millenium, the challenge is shifting to the development of therapy of these diseases. This review, in honour of Professor Alan Emery, explains how these advances have an impact in the clinical management of patients and head the promise the progress holds for the future.

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Citations

Jan 5, 2002·Journal of Physiology, Paris·Emmanuel ChaubourtSabine De La Porte
Jun 6, 2000·Neuromuscular Disorders : NMD·D Conte Camerino, A De Luca
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Aug 28, 2021·Life·Michael OgundeleYetrib Hathout

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