Challenges in rheumatic valvular disease: Surgical strategies for mitral valve preservation

Global Cardiology Science & Practice
Manuel J Antunes

Abstract

In developing countries, rheumatic fever and carditis still constitutes a major public health problem. Patients have special characteristics that differ from those with rheumatic mitral valve disease we still see in developed countries. They are usually young, poor, uneducated, and have low compliance to prophylaxis / therapy. In addition, they usually have great difficulty in accessing medical care. In these situations, the rate of complications associated to valve replacement is significantly increased. Alternatively, mitral valve repair is now known to achieve better long-term results in this pathology, but this was not widely recognized three or four decades ago, when first reports showed worse results after repair of rheumatic regurgitation than with degenerative valves. This has been reported by several groups in developing countries in different continents, with high incidence of repairs and excellent long term results. It is, therefore, becoming increasingly clear that, although, the results may not compare to those obtained with degenerative pathology, repair of rheumatic valves, when feasible, is the procedure of choice, especially in these underprivileged populations.

References

Sep 1, 1990·The Annals of Thoracic Surgery·C ZussaC Valfré
Jan 1, 1983·The Annals of Thoracic Surgery·R W FraterJ Strom
Oct 1, 1995·The Annals of Thoracic Surgery·A S KumarA Saxena
Nov 26, 2002·The Journal of Thoracic and Cardiovascular Surgery·Alexandre Ciappina HuebSérgio Almeida de Oliveira
Apr 12, 2005·The Journal of Thoracic and Cardiovascular Surgery·Sachin TalwarArkalgud Sampath Kumar
Aug 28, 2007·The Annals of Thoracic Surgery·Rachid ZegdiAlain Deloche
Jun 12, 2008·The Journal of Thoracic and Cardiovascular Surgery·Loris SalvadorCarlo Valfrè
Oct 31, 2008·International Heart Journal·Yao-Chang WangPyng-Jing Lin
Nov 26, 2009·The Journal of Thoracic and Cardiovascular Surgery·Daniel J DiBardinoLawrence H Cohn
Feb 24, 2012·Revista brasileira de cirurgia cardiovascular : órgão oficial da Sociedade Brasileira de Cirurgia Cardiovascular·Elaine Soraya Barbosa de Oliveira SeverinoDomingo Marcolino Braile
Jan 30, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Manuel J Antunes
Feb 15, 2013·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Jeswant DillonPaneer S Krishna Moorthy
Jun 27, 2013·World Journal for Pediatric & Congenital Heart Surgery·Bo RemenyiNigel Wilson

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Citations

Mar 1, 2019·Current Cardiology Reports·Nina C WunderlichRobert J Siegel
Mar 21, 2019·Revista Da Sociedade Brasileira De Medicina Tropical·Matheus Tozatto Baptista Coelho LealMaria Carmo Pereira Nunes
Oct 17, 2020·Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India·Hartzell Vernon Schaff, Anita Nguyen
May 4, 2021·Journal of Cardiac Surgery·Dominique VervoortA Thomas Pezzella
Dec 17, 2021·Texas Heart Institute Journal·Ikechukwu A NwaforMaureen N Nwafor

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