Challenges in the Analysis of Novel Flame Retardants in Indoor Dust: Results of the INTERFLAB 2 Interlaboratory Evaluation

Environmental Science & Technology
Lisa MelymukBrock Chittim

Abstract

The Interlaboratory Study of Novel Flame Retardants (INTERFLAB 2) was conducted by 20 laboratories in 12 countries to test the precision and accuracy of the analysis of 24 "novel" flame retardants (NFRs). Laboratories analyzed NFRs in injection-ready test mixtures, in extracts of residential dust, and in residential dust to evaluate the influence of dust handling and extraction. For test mixtures, mean reported concentrations of PBT, PBEB, EH-TBB, TBBPA, TBDP-TAZTO, TBOEP, α-TBCO, β-DBE-DBCH, and total HBCDD differed by >25% relative to reference values. Coefficients of variation were higher in dusts/dust extracts than in test mixtures. Concentrations among laboratories ranged over 3-4 orders of magnitude for HBB, TBP-DBPE, TBP-AE, and TDCIPP in dust extracts and dusts. Most laboratories produced repeatable dust concentrations, but differences reported in the literature among laboratories of <70% could be due to analytical variability, and the attribution of such differences to other causes should be made with caution. Most variations in accuracy and precision were introduced by matrix effects and/or sample processing, rather than instrumental analysis. We recommend recovery correction to improve accuracy. There is a need to im...Continue Reading

References

May 10, 2002·Chemosphere·Jacob de Boer, Wim P Cofino
Dec 31, 2003·Environmental Health Perspectives·Linda S Birnbaum, Daniele F Staskal
Nov 8, 2007·Analytical and Bioanalytical Chemistry·Thomas P J LinsingerAlmuth Liebich
Jul 2, 2008·Environmental Science & Technology·Naomi Lubick
Oct 16, 2008·Environmental Science & Technology·Mohamed Abou-Elwafa AbdallahAdrian Covaci
May 6, 2010·Talanta·Tinne GeensAdrian Covaci
Dec 21, 2010·Environment International·Adrian CovaciCynthia A de Wit
Dec 17, 2011·Journal of Chromatography. a·Alexandra PapachlimitzouRobin J Law
Nov 10, 2012·Journal of Biochemical and Molecular Toxicology·Heather B PatisaulHeather M Stapleton
Nov 29, 2012·Environmental Science & Technology·Robin E DodsonRuthann A Rudel
May 20, 2014·Chemosphere·Asa BradmanThomas E McKone
May 23, 2014·Environmental Science & Technology·Enrique CequierCathrine Thomsen
Feb 11, 2015·Environmental Science & Technology·Seth NewtonCynthia A de Wit
Jul 3, 2015·Analytical and Bioanalytical Chemistry·Lisa MelymukMiriam L Diamond
Jan 10, 2016·The Science of the Total Environment·Golnoush AbbasiMiriam L Diamond
Apr 14, 2017·Environmental Science & Technology·Robin E DodsonJoseph G Allen
Jun 19, 2017·Environment International·Martina VykoukalováJana Klánová

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