Challenges in the Management of Inverted Papilloma: A Review of 72 Revision Cases

The Laryngoscope
Gwijde F J P M AdriaensenWytske J Fokkens

Abstract

We report on the treatment outcome of endoscopically managed sinonasal inverted papilloma, focusing on revision cases. Our aim was to identify the properties of revision cases that affect treatment outcome by comparing them to primary cases in a single center. We propose using 5-fluorouracil (5-FU) in the postoperative management of inverted papilloma. A retrospective single-center case series. This study met the criteria for approval by the local medical ethics committee. We performed a retrospective chart review identifying patients operated on between January 2003 and September 2013. Data were collected about patient demographics, symptoms, tumor attachment site, imaging, intraoperative and pathological findings, surgical approaches, postoperative treatment, follow-up, and recurrence. One hundred and twenty-one (72 revision and 49 primary) cases were retrieved with a minimum follow-up of 1 year. Revision cases have significantly higher Krouse staging (P = 0.003), different distribution of tumor attachment sites, and higher recurrence rates. The recurrence rate was 4.1% for primary cases (mean follow-up 35.5 months) and 18.1% for revision cases (mean follow-up 45 months). Eight of the recurrent cases recurred within the first...Continue Reading

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Jul 13, 2017·The Laryngoscope·Robert Saddawi-KonefkaPhilip A Weissbrod
Dec 19, 2017·BioMed Research International·Marta Gamrot-WrzołMaciej Misiołek
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Dec 22, 2020·Allergy & Rhinology·Jeffrey D SuhBozena Wrobel
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