Challenges of implementing personalized (precision) medicine: a focus on diabetes

Personalized Medicine
Adriana Fodor, Eddy Karnieli

Abstract

The concept of personalized (precision) medicine (PM) emphasizes the scientific and technological innovations that enable the physician to tailor disease prediction, diagnosis and treatment to the individual patient, based on a personalized data-driven approach. The major challenge for the medical systems is to translate the molecular and genomic advances into clinical available means. Patients and healthcare providers, the pharmaceutical and diagnostic industries manifest a growing interest in PM. Multiple stakeholders need adaptation and re-engineering for successful clinical implementation of PM. Drawing primarily from the field of 'diabetes', this article will summarize the main challenges to implementation of PM into current medical practice and some of the approaches currently being implemented to overcome these challenges.

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Citations

Jul 27, 2017·Clinical and Translational Medicine·Enrico Capobianco
Aug 29, 2019·Drug Metabolism Reviews·Adriana FodorGabriela Roman
Nov 2, 2020·Life Sciences, Society and Policy·M Walid QoronflehSaid Ismail

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Methods Mentioned

BETA
genotyping
pharmacotherapy
exome

Software Mentioned

PGx
IGNITE ( Implementing
IGNITE
GoDARTS
ClinVar
GeNomics In pracTicE

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