Challenges with colorectal cancer staging: results of an international study

Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc
Dipti M KaramchandaniDavid K Driman

Abstract

Challenges exist with standardized colorectal cancer reporting despite adoption of the American Joint Committee on Cancer-Staging Manual 8th edition. We performed this study to gauge current practice patterns among a diverse group of surgical pathologists. A web-based questionnaire depicting problematic issues and images related to colorectal carcinoma staging was circulated among 118 surgical pathologists and their responses were correlated with their geographic location (North America vs. Europe vs. others), nature of practice (academic vs. community), the sign-out model (gastrointestinal subspecialty vs. general surgical pathology), and years of professional experience. We found that a substantial number of practicing pathologists ignore recommended-staging criteria in specific settings, particularly with respect to assessment of advanced T stage. Tumors that communicated with the serosa through inflammatory foci were staged as pT3 (49%) or pT4a (51%) by nearly equal numbers of pathologists regardless of level of experience, the sign-out model, or geographic location. Only 65% assigned T stage and margin status based on extent of viable tumor in the neoadjuvant setting. One-third of pathologists, particularly those in Europe...Continue Reading

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Citations

Jul 17, 2020·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Robert Pantaleon VasquezDipti M Karamchandani
Sep 16, 2020·The American Journal of Surgical Pathology·Nicole C PanarelliMaria Westerhoff
Jan 19, 2021·International Journal of Surgical Pathology·Whayoung LeeXiaodong Li
Sep 5, 2020·Archives of Pathology & Laboratory Medicine·Julia R NasoDavid F Schaeffer

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Methods Mentioned

BETA
surgical resection
dissect
dissects
dissection
dissections

Software Mentioned

SAS

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