Change in anxiety sensitivity and substance use coping motives as putative mediators of treatment efficacy among substance users

Behaviour Research and Therapy
Kate B Wolitzky-TaylorMichelle G Craske

Abstract

Anxiety sensitivity and coping motives for substance use are processes implicated in anxiety and substance use disorder (SUD) comorbidity, and are malleable treatment targets. Little is known about whether changes in anxiety sensitivity or coping motives during cognitive behavioral therapy (CBT) for anxiety disorders (with or without CBT for SUD) mediate substance use outcomes among patients with comorbid anxiety disorders and SUD. We examined whether changes in anxiety sensitivity and coping motives during treatment for comorbid SUD and anxiety disorders (either CBT for SUD only or CBT for SUD and anxiety disorders) were associated with substance use outcomes. Repeated measurements of anxiety sensitivity and coping motives throughout treatment were examined from a randomized clinical trial comparing usual, CBT-based treatment at a substance use disorder specialty clinic (UC) to that usual care plus a brief CBT for anxiety program for patients with comorbid anxiety and substance use disorders (CALM ARC). Anxiety sensitivity decline during treatment was significantly steeper among those who received CALM ARC than those in UC. Decreases in anxiety sensitivity mediated the effect of treatment group on alcohol use following treatme...Continue Reading

Associated Clinical Trials

Citations

Sep 29, 2020·Addictive Behaviors·Georgia StathopoulouMichael W Otto
Mar 30, 2021·Alcohol and Alcoholism : International Journal of the Medical Council on Alcoholism·Victoria R VotawKatie Witkiewitz
Jul 3, 2021·Journal of Substance Abuse Treatment·Blake T HiltonR Kathryn McHugh
Jul 31, 2021·Current Addiction Reports·Julia E SwanKatie Witkiewitz

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