Change in knee contact force with simulated change in body weight

Computer Methods in Biomechanics and Biomedical Engineering
Brian A KnarrJoseph A Zeni

Abstract

The relationship between obesity, weight gain and progression of knee osteoarthritis is well supported, suggesting that excessive joint loading may be a mechanism responsible for cartilage deterioration. Examining the influence of weight gain on joint compressive forces is difficult, as both muscles and ground reaction forces can have a significant impact on the forces experienced during gait. While previous studies have examined the relationship between body weight and knee forces, these studies have used models that were not validated using experimental data. Therefore, the objective of this study was to evaluate the relationship between changes in body weight and changes in knee joint contact forces for an individual's gait pattern using musculoskeletal modeling that is validated against known internal compressive forces. Optimal weighting constants were determined for three subjects to generate valid predictions of knee contact forces (KCFs) using in vivo data collection with instrumented total knee arthroplasty. A total of five simulations per walking trial were generated for each subject, from 80% to 120% body weight in 10% increments, resulting in 50 total simulations. The change in peak KCF with respect to body weight w...Continue Reading

References

Jun 30, 2005·Arthritis and Rheumatism·Stephen P MessierPaul DeVita
Nov 21, 2007·IEEE Transactions on Bio-medical Engineering·Scott L DelpDarryl G Thelen
Feb 28, 2009·Arthritis and Rheumatism·J NiuD T Felson
Dec 14, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Benjamin J FreglyDarryl D D'Lima
Dec 31, 2011·Gait & Posture·Katherine M SteeleScott L Delp
Jul 5, 2012·The American Journal of Clinical Nutrition·Prachi SinghMichael D Jensen
Feb 26, 2013·Arthritis and Rheumatism·Frank C KoMarjolein C H van der Meulen
Mar 13, 2014·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Matthew S DemersScott L Delp

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