Change in size of lesions over 3 weeks after radiofrequency ablation of left ventricle

Journal of Cardiovascular Electrophysiology
Pramesh KovoorDavid L Ross

Abstract

The initial success or failure of radiofrequency ablation (RFA) does not always reflect the long-term outcome that can lead to complications such as late atrioventricular block or recurrence of accessory pathways. We hypothesize that these occurrences may be due to a change in lesion size over time. Intramural RFAs were performed on five greyhounds at thoracotomy using an epicardial approach into the left ventricular (LV) wall. Twenty-one gauge needle electrode ablations were created in the anterior aspect of the left ventricle. Radiofrequency energy was delivered at 600 Hz for 60 seconds and at an electrode temperature of 90 degrees C. Eight ablations were created in each greyhound and the chest was closed. After 3 weeks, a further eight ablations were created under the same conditions in the lateral aspect of the LV, ensuring they were well away from the chronic lesions, and the dogs were sacrificed an hour later. All lesions were removed, stained with Gomori Trichrome and measured. There was no significant difference in lesion size detected in the 1-hour-old lesions compared with 3-week-old lesions. Acute lesions were well demarcated by an area of fibrous scar and a central necrotic region. Chronic lesions showed chronic inf...Continue Reading

References

Jun 1, 1989·American Heart Journal·M E RingM Lev
Dec 17, 1983·Lancet·G A Silver
Feb 1, 1983·Experimental and Molecular Pathology·E H Silver, S Szabo
Nov 1, 1993·Pacing and Clinical Electrophysiology : PACE·M DickB Armstrong
Apr 1, 1993·Pacing and Clinical Electrophysiology : PACE·K M Stein, B B Lerman
May 1, 1993·Pacing and Clinical Electrophysiology : PACE·J J LangbergF Morady
Mar 1, 1996·The American Journal of Medicine·G N Kay, V J Plumb
Apr 17, 2001·Cardiology in Review·P Angkeow, H G Calkins
Nov 7, 2002·Circulation Journal : Official Journal of the Japanese Circulation Society·Masafumi TakahashiKazuyuki Shimada
Jan 1, 1951·British Heart Journal·I LODGE-PATCH
Jun 11, 2004·Pacing and Clinical Electrophysiology : PACE·Pramesh KovoorDavid Ross

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Citations

Jun 28, 2014·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Jagdeep Singh VirkBhik Kotecha
Sep 25, 2008·Pacing and Clinical Electrophysiology : PACE·André D'AvilaVivek Y Reddy
Mar 29, 2018·Biophysical Journal·Theresa H LyeChristine P Hendon

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