PMID: 11606173Oct 19, 2001Paper

Change of glycaemic status in Chinese subjects with impaired fasting glycaemia

Diabetic Medicine : a Journal of the British Diabetic Association
G T KoC S Cockram

Abstract

To examine the risk of progression to diabetes in Chinese subjects with impaired fasting glycaemia (IFG) or normal fasting glucose (NFG). Between 1988 and 1996, 657 Hong Kong Chinese subjects underwent annual screening, using an oral glucose tolerance test, until they had developed diabetes, or until June 1997, when the data were analysed. All subjects had a risk factor associated with the development of diabetes such as a history of gestational diabetes or a family history of diabetes. The follow-up interval for the subjects ranged from 0.87 to 8.54 years and of the 657, 319 had fasting plasma glucose levels of < 7.0 mmol/L where a fasting glucose level of > or = 7.0 mmol/L was used to diagnose diabetes Of the 319 nondiabetic subjects, 55 had IFG and 264 had NFG. After a median follow-up of 1.12 years (range: 0.87-8.54 years), 27 progressed to diabetes. The Kaplan-Meier analysis of progression to diabetes showed significant differences between subjects with IFG and subjects with NFG. Using Cox regression analysis, IFG (beta = 3.51, SE = 1.63, P = 0.032) and smoking (beta = 3.60, SE = 1.50, P = 0.017) were found to be independently associated with progression to diabetes. In Hong Kong Chinese with risk factors for glucose intol...Continue Reading

Associated Clinical Trials

References

Dec 8, 1988·The New England Journal of Medicine·M F SaadP H Bennett
Apr 1, 1982·Diabetologia·L H Toledo-Pereyra
Nov 1, 1996·Diabetic Medicine : a Journal of the British Diabetic Association·K G Alberti
Nov 22, 1997·International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity·G T KoC S Cockram
Jun 18, 1999·Diabetes Care·R C Perry, A D Baron

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Citations

May 8, 2002·Diabetes/metabolism Research and Reviews
May 22, 2003·Diabetes Research and Clinical Practice·Kow-Tong ChenK M V Narayan
Jan 10, 2003·Circulation Journal : Official Journal of the Japanese Circulation Society·Nobuo NakamuraOsamu Satani
Feb 6, 2008·Journal of Preventive Medicine and Public Health = Yebang Ŭihakhoe Chi·Hong Dae UmYeon Soo Kim
Jul 20, 2005·Diabetes Research and Clinical Practice·Liang-Kung ChenShu-Ti Chiou
Aug 10, 2011·The American Journal of Cardiology·Ralph A DeFronzo, Muhammad Abdul-Ghani
Oct 30, 2018·The Cochrane Database of Systematic Reviews·Bernd RichterYemisi Takwoingi
Oct 15, 2005·Nursing Research·Chen-Yen Wang, Siu Ming Alain Chan

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