PMID: 6411866Aug 1, 1983Paper

Change of seizure frequency in pregnant epileptic women

Journal of Neurology, Neurosurgery, and Psychiatry
D SchmidtD Janz

Abstract

The effect of pregnancy on seizure frequency was monitored prospectively in 136 pregnancies of 122 epileptic women. Pregnancy did not influence the seizure frequency in 68 pregnancies (50%). In 50 pregnancies (37%) the number of seizures increased during pregnancy or puerperium. The seizure frequency decreased in 18 pregnancies (13%). In 34 out of 50 pregnancies (68%) the increase was associated with non-compliance with the drug regimen or sleep deprivation. In seven out of 18 pregnancies (39%) improvement was related to correction of non-compliance or sleep deprivation during the pregestational nine months. Insufficiently low plasma concentrations of antiepileptic drugs were found in 47% of the women with uncontrolled epilepsy during pregnancy. The course of epilepsy during pregnancy is primarily influenced by non-compliance, sleep deprivation during pregnancy, and inadequate therapy before and during pregnancy. With good medical attention pregnancy itself seems to have only a minimal influence on the course of epilepsy.

References

Jun 1, 1982·American Journal of Ophthalmology·J B Moloney, M I Drury
Feb 1, 1981·Epilepsia·E H Reynolds, S D Shorvon
Feb 1, 1982·The Tohoku Journal of Experimental Medicine·H HoshiaiM Suzuki

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Citations

Jul 1, 1996·Indian Journal of Pediatrics·S K TamerS Jaiswal
Dec 6, 2001·Current Treatment Options in Neurology·Michiko Kimura Bruno, Cynthia L. Harden
Jul 1, 1996·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·H SawhneyI M Sawhney
Nov 3, 1990·Lancet
Jan 1, 1989·Epilepsy Research·V G KaliaperumalK S Mani
May 20, 1998·Clinical Therapeutics·S Kaneko
Jun 27, 1998·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J M Swartjes, H P van Geijn
May 19, 2001·Neurologic Clinics·N Foldvary
Jun 1, 1993·Seizure : the Journal of the British Epilepsy Association·P Crawford
Feb 28, 1985·The New England Journal of Medicine·D J Dalessio
Apr 9, 2013·Clinical Obstetrics and Gynecology·Sarah C Campbell, Michael G Spigarelli
Aug 1, 1993·Journal of Clinical Pharmacy and Therapeutics·N M Graves, I E Leppik
Aug 1, 1993·Australian and New Zealand Journal of Medicine·C J Kilpatrick, J L Hopper
May 1, 1985·Epilepsia·R H Levy, D Schmidt
Jan 1, 1991·Epilepsia·M S Yerby
Jan 1, 1993·Epilepsia·O Devinsky, J K Penry
Nov 23, 2007·Epilepsia·Frank J E VajdaMervyn Eadie
Jan 15, 2009·Epilepsia·Umberto AgugliaAlberto Verrotti
Mar 21, 2012·Epilepsia·Sanjeev V ThomasJ Sucharitha Devi
Dec 1, 1992·Acta Neurologica Scandinavica·D BattinoF Molteni
Feb 21, 1987·British Medical Journal·A Hopkins
Sep 2, 1989·BMJ : British Medical Journal·M Saunders
Aug 11, 2000·Pharmacotherapy·M S Yerby
Aug 23, 2005·Expert Opinion on Drug Safety·Stephen J Hunt, Jim I Morrow
Sep 1, 1987·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·N J Conley, E Olshansky
Mar 31, 2009·Epilepsy & Behavior : E&B·Anne Sabers
Apr 10, 2003·Mayo Clinic Proceedings·Joyce Liporace, Anelyssa D'Abreu
Nov 13, 2007·Epilepsy & Behavior : E&B·Peter W KaplanJacki C Gordon
Nov 26, 2015·Critical Care Clinics·Mauricio Ruiz Cuero, Panayiotis N Varelas
Sep 1, 1988·Acta Neurologica Scandinavica·I O GjerdeM Ulstein
Jul 17, 2001·Seminars in Perinatology·M S Yerby
Jan 1, 1991·Annals of Emergency Medicine·A Jagoda, S Riggio
Jun 18, 2004·Obstetrics and Gynecology Clinics of North America·E Rebecca Pschirrer
Oct 12, 2004·Neurologic Clinics·Page B Pennell
Jan 22, 2002·Best Practice & Research. Clinical Obstetrics & Gynaecology·S A Lowe
Dec 1, 1996·Seizure : the Journal of the British Epilepsy Association·A J RussellM J Brodie
Dec 26, 2007·Seizure : the Journal of the British Epilepsy Association·Eylert Brodtkorb, Arne Reimers
Aug 24, 1999·Seizure : the Journal of the British Epilepsy Association·P CrawfordJ Morrow
Jan 19, 2007·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·Jana Velísková

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